Lewis acid catalyst free synthesis of benzimidazoles and formamidines in 1,1,1,3,3,3-hexafluoro-2-propanol

被引：63

作者：

Khaksar, Samad ^{[1
]}

Heydari, Akbar ^{[2
]}

Tajbakhsh, Mahmood ^{[3
]}

Vandat, Seyed Mohammad ^{[1
]}

机构：

[1] Islamic Azad Univ, Ayatollah Amoli Branch, Dept Chem, Amol, Iran

[2] Tarbiat Modares Univ, Dept Chem, Tehran, Iran

[3] Mazandaran Univ, Dept Chem, Babol Sar, Iran

来源：

JOURNAL OF FLUORINE CHEMISTRY | 2010年 / 131卷 / 12期

关键词：

Benzimidazole; Formamidine; Hexafluoroisopropanol; Hydrogen bonding; ONE-POT SYNTHESIS; IMIDIC ESTERS; ONE-STEP; AMIDINES; DERIVATIVES; AMINES; EFFICIENT; DESIGN; 2-ALKYLBENZIMIDAZOLES; BENZOXAZOLES;

D O I：

10.1016/j.jfluchem.2010.10.002

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A simple, inexpensive, environmentally friendly and efficient route for the synthesis of benzimidazole and formamidine derivatives by the reaction of O-phenylenediamines or amines with orthoesters using hexafluoroisopropanol as a solvent/catalyst is described. (C) 2010 Elsevier B.V. All rights reserved.

引用

页码：1377 / 1381

页数：5

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