Current debate on the use of antibiotic prophylaxis for caesarean section

被引：72

作者：

Lamont, R. F. ^{[1
,2
,3
]}

Sobel, J. D. ^{[4
]}

Kusanovic, J. P. ^{[1
,2
,3
]}

Vaisbuch, E. ^{[1
,2
,3
]}

Mazaki-Tovi, S. ^{[1
,2
,3
]}

Kim, S. K. ^{[1
,2
]}

Uldbjerg, N. ^{[1
,2
]}

Romero, R. ^{[1
,2
,5
]}

机构：

[1] Wayne State Univ, Hutzel Womens Hosp, NICHD, Perinatol Res Branch,NIH,DHHS, Detroit, MI 48201 USA

[2] NICHD, Perinatol Res Branch, NIH, DHHS, Bethesda, MD USA

[3] Wayne State Univ, Sch Med, Dept Obstet & Gynecol, Detroit, MI 48201 USA

[4] Wayne State Univ, Sch Med, Dept Infect Dis, Detroit, MI 48201 USA

[5] Wayne State Univ, Ctr Mol Med & Genet, Detroit, MI 48201 USA

来源：

BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY | 2011年 / 118卷 / 02期

关键词：

Antibiotics; caesarean section; endometritis; pregnancy; prophylaxis; surgical site infections; SURGICAL-SITE INFECTIONS; HIGH-RISK PATIENTS; EARLY POSTPARTUM ENDOMETRITIS; HOSPITAL-ACQUIRED INFECTIONS; RANDOMIZED CONTROLLED-TRIAL; WOUND-INFECTION; POSTDISCHARGE SURVEILLANCE; MATERNAL MORBIDITY; ANTIMICROBIAL PROPHYLAXIS; UREAPLASMA-UREALYTICUM;

D O I：

10.1111/j.1471-0528.2010.02729.x

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Caesarean delivery is frequently complicated by surgical site infections, endometritis and urinary tract infection. Most surgical site infections occur after discharge from the hospital, and are increasingly being used as performance indicators. Worldwide, the rate of caesarean delivery is increasing. Evidence-based guidelines recommended the use of prophylactic antibiotics before surgical incision. An exception is made for caesarean delivery, where narrow-range antibiotics are administered after umbilical cord clamping because of putative neonatal benefit. However, recent evidence supports the use of pre-incision, broad-spectrum antibiotics, which result in a lower rate of maternal morbidity with no disadvantage to the neonate.

引用

页码：193 / 201

页数：9