SAMHD1 expression in blood cells of HIV-1 elite suppressors and viraemic progressors

被引:8
作者
Buchanan, Erin L. [1 ]
McAlexander, Melissa A. [1 ]
Witwer, Kenneth W. [1 ]
机构
[1] Johns Hopkins Univ, Sch Med, Dept Mol & Comparat Pathobiol, Baltimore, MD 21218 USA
关键词
elite controllers; PBMCs; interferon; IFN; RESTRICTION; PHOSPHORYLATION; CONTROLLERS; INFECTION;
D O I
10.1093/jac/dku428
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
引用
收藏
页码:954 / 956
页数:4
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共 10 条
[1]   Expression profile of host restriction factors in HIV-1 elite controllers [J].
Abdel-Mohsen, Mohamed ;
Raposo, Rui Andre Saraiva ;
Deng, Xutao ;
Li, Manqing ;
Liegler, Teri ;
Sinclair, Elizabeth ;
Salama, Mohamed S. ;
Ghanem, Hussam El-Din A. ;
Hoh, Rebecca ;
Wong, Joseph K. ;
David, Michael ;
Nixon, Douglas F. ;
Deeks, Steven G. ;
Pillai, Satish K. .
RETROVIROLOGY, 2013, 10
[2]   The implications of viral reservoirs on the elite control of HIV-1 infection [J].
Buckheit, Robert W., III ;
Salgado, Maria ;
Martins, Karen O. ;
Blankson, Joel N. .
CELLULAR AND MOLECULAR LIFE SCIENCES, 2013, 70 (06) :1009-1019
[3]   Phosphorylation of SAMHD1 by Cyclin A2/CDK1 Regulates Its Restriction Activity toward HIV-1 [J].
Cribier, Alexandra ;
Descours, Benjamin ;
Chaves Valadao, Ana Luiza ;
Laguette, Nadine ;
Benkirane, Monsef .
CELL REPORTS, 2013, 3 (04) :1036-1043
[4]   GTP activator and dNTP substrates of HIV-1 restriction factor SAMHD1 generate a long-lived activated state [J].
Hansen, Erik C. ;
Seamon, Kyle J. ;
Cravens, Shannen L. ;
Stivers, James T. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (18) :E1843-E1851
[5]   CLONING AND CHARACTERIZATION OF A NOVEL CDNA THAT IS IFN-GAMMA-INDUCED IN MOUSE PERITONEAL-MACROPHAGES AND ENCODES A PUTATIVE GTP-BINDING PROTEIN [J].
LAFUSE, WP ;
BROWN, D ;
CASTLE, L ;
ZWILLING, BS .
JOURNAL OF LEUKOCYTE BIOLOGY, 1995, 57 (03) :477-483
[6]   Increased expression of SAMHD1 in a subset of HIV-1 elite controllers [J].
Riveira-Munoz, Eva ;
Ruiz, Alba ;
Pauls, Eduardo ;
Permanyer, Marc ;
Badia, Roger ;
Mothe, Beatriz ;
Crespo, Manel ;
Clotet, Bonaventura ;
Brander, Christian ;
Ballana, Ester ;
Este, Jose A. .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2014, 69 (11) :3057-3060
[7]   miRNA Profiles of Monocyte-Lineage Cells Are Consistent with Complicated Roles in HIV-1 Restriction [J].
Sisk, Jeanne M. ;
Clements, Janice E. ;
Witwer, Kenneth W. .
VIRUSES-BASEL, 2012, 4 (10) :1844-1864
[8]   SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4+ T-lymphocytes cannot be upregulated by interferons [J].
St Gelais, Corine ;
de Silva, Suresh ;
Amie, Sarah M. ;
Coleman, Christopher M. ;
Hoy, Heather ;
Hollenbaugh, Joseph A. ;
Kim, Baek ;
Wu, Li .
RETROVIROLOGY, 2012, 9
[9]   The Retroviral Restriction Ability of SAMHD1, but Not Its Deoxynucleotide Triphosphohydrolase Activity, Is Regulated by Phosphorylation [J].
White, Tommy E. ;
Brandariz-Nunez, Alberto ;
Valle-Casuso, Jose Carlos ;
Amie, Sarah ;
Laura Anh Nguyen ;
Kim, Baek ;
Tuzova, Marina ;
Diaz-Griffero, Felipe .
CELL HOST & MICROBE, 2013, 13 (04) :441-451
[10]   Relationships of PBMC microRNA expression, plasma viral load, and CD4+ T-cell count in HIV-1-infected elite suppressors and viremic patients [J].
Witwer, Kenneth W. ;
Watson, Andria K. ;
Blankson, Joel N. ;
Clements, Janice E. .
RETROVIROLOGY, 2012, 9