Different extracellular domains of the gastrin-releasing peptide receptor (GRP-R) are crucial for determining affinity for peptide agonists and peptide antagonists.

被引：0
|
作者：
Katsuno, T
Donohue, PJ
Akeson, MA
Battey, JF
Jensen, RT
机构：
[1] NIDDK, DIGEST DIS BRANCH, NIH, BETHESDA, MD USA
[2] NIDCD, NIH, MOL BIOL LAB, ROCKVILLE, MD USA
来源：
GASTROENTEROLOGY | 1997年 / 112卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：A1161 / A1161
页数：1
相关论文
共 50 条
  • [1] Comparison of the role of extracellular domains of the gastrin-releasing peptide receptor (GRP-R) and the neuromedin B receptor (NMB-R) for determining affinity for peptide antagonists
    Tokita, K
    Katsuno, T
    Llinares, M
    Martinez, J
    Battey, JF
    Jensen, RT
    GASTROENTEROLOGY, 1999, 116 (04) : A651 - A651
  • [2] Elucidation of receptor domains of gastrin-releasing peptide receptor (GRPR) determining high selectivity for peptide antagonists.
    Katsuno, T
    Pradhan, TK
    Mantey, SA
    Donohue, PJ
    Battey, JF
    Coy, DH
    Jensen, RT
    GASTROENTEROLOGY, 1998, 114 (04) : A1153 - A1153
  • [3] Effect of gastrin-releasing peptide receptor (GRP-R) number on receptor affinity, coupling, degradation and receptor modulation.
    Tsuda, T
    Hou, W
    Jensen, RT
    GASTROENTEROLOGY, 1997, 112 (04) : A488 - A488
  • [4] Gastrin-releasing peptide (GRP) with its receptor (GRP-R) is a mitogen and morphogen in colon cancer.
    Carroll, RE
    Matkowskyj, KA
    Battey, JF
    Benya, RV
    GASTROENTEROLOGY, 2000, 118 (04) : A558 - A558
  • [5] Molecular basis for selectivity of high affinity peptide antagonists for the gastrin-releasing peptide receptor
    Tokita, K
    Katsuno, T
    Hocart, SJ
    Coy, DH
    Llinares, M
    Martinez, J
    Jensen, RT
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (39) : 36652 - 36663
  • [6] Different highly selective gastrin-releasing peptide receptor (GRPR) peptide antagonists interact with different receptor domains.
    Tokita, M
    Katsuno, T
    Llinares, M
    Martinez, J
    Jensen, RT
    GASTROENTEROLOGY, 2000, 118 (04) : A310 - A310
  • [7] Identification of key amino acids in the gastrin-releasing peptide receptor (GRPR) responsible for high affinity binding of gastrin-releasing peptide (GRP)
    Nakagawa, T
    Hocart, SJ
    Schumann, M
    Tapia, JA
    Mantey, SA
    Coy, DH
    Tokita, K
    Katsuno, T
    Jensen, RT
    BIOCHEMICAL PHARMACOLOGY, 2005, 69 (04) : 579 - 593
  • [8] INTERNALIZATION OF THE GASTRIN-RELEASING PEPTIDE RECEPTOR (GRP-R) IS NOT TOTALLY DEPENDENT ON PHOSPHOLIPASE-C ACTIVATION
    BENYA, RV
    AKESON, M
    BATTEY, JF
    JENSEN, RT
    GASTROENTEROLOGY, 1994, 106 (04) : A799 - A799
  • [9] Targeting the Gastrin-Releasing Peptide Receptor (GRP-R) in Cancer Therapy: Development of Bombesin-Based Peptide-Drug Conjugates
    Gomena, Jacopo
    Vari, Balazs
    Olah-Szabo, Rita
    Biri-Kovacs, Beata
    Bosze, Szilvia
    Borbely, Adina
    Soos, Adam
    Randelovic, Ivan
    Tovari, Jozsef
    Mezo, Gabor
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (04)
  • [10] Gastrin-releasing peptide (GRP) with its receptor (GRP-R) is an autocrine growth factor important for villous development.
    Carroll, RE
    Matkowskyj, KA
    Battey, JF
    Benya, RV
    GASTROENTEROLOGY, 2000, 118 (04) : A436 - A436
12345