Advances in Nanoliposomes for the Diagnosis and Treatment of Liver Cancer

被引:36
作者
Li, Yitong [1 ]
Zhang, Ruihang [2 ]
Xu, Zhen [1 ]
Wang, Zhicheng [1 ]
机构
[1] Jilin Univ, NHC Key Lab Radiobiol, Sch Publ Hlth, 1163 Xinmin St, Changchun 130021, Jilin, Peoples R China
[2] Henan Univ Tradit Chinese Med, Clin Med Coll 2, Zhengzhou 450052, Henan, Peoples R China
来源
INTERNATIONAL JOURNAL OF NANOMEDICINE | 2022年 / 17卷
关键词
liver targeting; nanotherapeutics; nanocarriers; multimodal imaging; nanomedicine; diagnostic treatment integration; INTENSITY FOCUSED ULTRASOUND; SMALL INTERFERING RNA; HEPATOCELLULAR-CARCINOMA; DRUG-DELIVERY; HEPATITIS-B; TRANSARTERIAL CHEMOEMBOLIZATION; PHOTODYNAMIC THERAPY; LIPID NANOPARTICLES; SYNERGISTIC THERAPY; TRIGGERED RELEASE;
D O I
10.2147/IJN.S349426
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
The mortality rate of liver cancer is gradually increasing worldwide due to the increasing risk factors such as fatty liver, diabetes, and alcoholic cirrhosis. The diagnostic methods of liver cancer include ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI), among others. The treatment of liver cancer includes surgical resection, transplantation, ablation, and chemoembolization; however, treatment still faces multiple challenges due to its insidious development, high rate of recurrence after surgical resection, and high failure rate of transplantation. The emergence of liposomes has provided new insights into the treatment of liver cancer. Due to their excellent carrier properties and maneuverability, liposomes can be used to perform a variety of functions such as aiding in imaging diagnoses, combinatorial therapies, and integrating disease diagnosis and treatment. In this paper, we further discuss such advantages.
引用
收藏
页码:909 / 925
页数:17
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