New jacaranone glucoside from Jacaranda oxyphylla leaves

被引：6

作者：

Pereira, V. V. ^{[1
,2
]}

Duarte, L. P. ^{[1
]}

Silva, R. R. ^{[3
]}

Takahashi, J. A. ^{[1
]}

机构：

[1] Univ Fed Minas Gerais, Dept Chem, Belo Horizonte, MG, Brazil

[2] Univ Fed Minas Gerais, Fac Pharm, Belo Horizonte, MG, Brazil

[3] Univ Fed Vales Jequitinhonha & Mucuri, Dept Chem, Diamantina, Brazil

来源：

NATURAL PRODUCT RESEARCH | 2016年 / 30卷 / 21期

关键词：

Bignoniaceae; Jacaranda oxyphylla; quinoid; antiacetylcholinesterase activity; SENECIO-SCANDENS; FLAVONOIDS; MIMOSAEFOLIA; BIGNONIACEAE; GLYCOSIDES; PLANTS; DC;

D O I：

10.1080/14786419.2016.1195378

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Jacaranda oxyphylla Cham. is popularly known as caroba-de-SAo-Paulo' and it is used in traditional medicine for microbial infections. A new phytoquinoid (/-glucoside-4-phenylacetate-6-(1-hydroxy-4-oxo-2,5-cyclohexadiene-1-acetate) (1) was isolated from J. oxyphylla leaves, together with three known compounds: quercetin-3-O--d-galactoside (2), verbascoside (3) and polystyrene (4). Their chemical structures were elucidated using spectroscopic techniques and by comparison with the related known compounds. In addition, it was found a pronounced acetylcholinesterase inhibitory activity for the quinoid 1 (100.0 +/- 0.8%) and phenolic compounds 2 and 3 (99.9 +/- 0.7 and 99.3 +/- 0.5%, respectively), if compared to the standard eserine (92.7 +/- 0.4%), that was analysed by a microplate spectrophotometer. [GRAPHICS] .

引用

页码：2421 / 2428

页数：8

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