Genetic polymorphisms of matrix metalloproteinases in lung, breast and colorectal cancer

被引：48

作者：

Decock, J. ^{[1
]}

Paridaens, R. ^{[1
,2
]}

Ye, S. ^{[3
]}

机构：

[1] Katholieke Univ Leuven, Katholieke Univ Leuven Hosp, Dept Oncol, Expt Oncol Lab, Louvain, Belgium

[2] Katholieke Univ Leuven Hosp, Multidisciplinary Breast Ctr, Louvain, Belgium

[3] Univ London, Sch Med, William Harvey Res Inst, Dept Clin Pharmacol, London WC1E 7HU, England

来源：

CLINICAL GENETICS | 2008年 / 73卷 / 03期

关键词：

breast cancer; colorectal cancer; lung cancer; matrix metalloproteinases; polymorphism; SNP; survival; susceptibility;

D O I：

10.1111/j.1399-0004.2007.00946.x

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The matrix metalloproteinases (MMPs) can degrade various components of the extracellular matrix and are implicated in the development and progression of cancer. There is evidence suggesting an association of MMP gene polymorphisms with cancer susceptibility and/or metastasis. This paper reviews the findings on several single nucleotide polymorphisms in the collagenase, stromelysin and gelatinase genes in lung cancer, breast cancer and colorectal cancer.

引用

页码：197 / 211

页数：15

共 92 条

[1] The role of genetic variants of matrix metalloproteinases in coronary and carotid atherosclerosis [J].

Abilleira, Sonia ;

Bevan, Steve ;

Markus, Hugh S. .

JOURNAL OF MEDICAL GENETICS, 2006, 43 (12) :897-901

[2] Expression of matrix metalloproteinase 8 (MMP-8) and tyrosinase-related protein-1 (TYRP-1) correlates with the absence of metastasis in an isogenic human breast cancer model [J].

Agarwal, D ;

Goodison, S ;

Nicholson, B ;

Tarin, D ;

Urquidi, V .

DIFFERENTIATION, 2003, 71 (02) :114-125

[3] Loss of collagenase-2 confers increased skin tumor susceptibility to male mice [J].

Balbín, M ;

Fueyo, A ;

Tester, AM ;

Pendás, AM ;

Pitiot, AS ;

Astudillo, A ;

Overall, CM ;

Shapiro, SD ;

López-Otín, C .

NATURE GENETICS, 2003, 35 (03) :252-257

[4]

Biondi ML, 2000, CLIN CHEM, V46, P2023

[5] A single nucleotide polymorphism in the p53 pathway interacts with gender, environmental stresses and tumor genetics to influence cancer in humans [J].

Bond, G. L. ;

Levine, A. J. .

ONCOGENE, 2007, 26 (09) :1317-1323

[6] Identification and analysis of expression of human VACM-1, a cullin gene family member located on chromosome 11q22-23 [J].

Byrd, PJ ;

Stankovic, T ;

McConville, CM ;

Smith, AD ;

Cooper, PR ;

Taylor, AMR .

GENOME RESEARCH, 1997, 7 (01) :71-75

[7] Assessment of two flexible and compatible SNP genotyping platforms:: TaqMan® SNP genotyping assays and the SNPlex™ genotyping system [J].

De La Vega, FA ;

Lazaruk, KD ;

Rhodes, MD ;

Wenz, MH .

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2005, 573 (1-2) :111-135

[8] Association of matrix metalloproteinase-8 gene variation with breast cancer prognosis [J].

Decock, Julie ;

Long, Ji-Rong ;

Laxton, Ross C. ;

Shu, Xiao-Ou ;

Hodgkinson, Conrad ;

Hendrickx, Wouter ;

Pearce, Eve G. ;

Gao, Yu-Tang ;

Pereira, Andresa C. ;

Paridaens, Robert ;

Zheng, Wei ;

Ye, Shu .

CANCER RESEARCH, 2007, 67 (21) :10214-10221

[9] Matrix metalloproteinases and tumor metastasis [J].

Deryugina, EI ;

Quigley, JP .

CANCER AND METASTASIS REVIEWS, 2006, 25 (01) :9-34

[10]

Elander N, 2006, ANTICANCER RES, V26, P791

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