Effects of dietary Hericium erinaceus powder on growth, hematology, disease resistance, and expression of genes related immune response against thermal challenge of Nile tilapia (Oreochromis niloticus)

被引：12

作者：

Khieokhajonkhet, Anurak ^{[1
,2
,6
]}

Aeksiri, Niran ^{[1
,2
]}

Ratanasut, Kumrop ^{[1
,2
]}

Kannika, Korntip ^{[3
]}

Suwannalers, Piluntasoot ^{[4
]}

Tatsapong, Pattaraporn ^{[2
]}

Inyawilert, Wilasinee ^{[1
,2
]}

Kaneko, Gen ^{[5
]}

机构：

[1] Naresuan Univ, Fac Agr Nat Resources & Environm, Ctr Excellence Res Agr Biotechnol, Phitsanulok 65000, Thailand

[2] Naresuan Univ, Fac Agr Nat Resources & Environm, Dept Agr Sci, Phitsanulok 65000, Thailand

[3] Univ Phayao, Sch Agr & Nat Resources, Phayao 56000, Thailand

[4] Chiang Mai Rajabhat Univ, Fac Agr Technol, Chiang Mai 50300, Thailand

[5] Univ Houston Victoria, Coll Nat & Appl Sci, 3007 N Ben Wilson, Victoria, TX 77901 USA

[6] Naresuan Univ, Fac Agr Nat Resources & Environm, Dept Agr Sci, 99 M 1, Muang 65000, Phitsanulok Pro, Thailand

来源：

ANIMAL FEED SCIENCE AND TECHNOLOGY | 2022年 / 290卷

关键词：

Mushroom; Immunity; Blood; Thermal stress; Nile tilapia; AEROMONAS-HYDROPHILA; BIOCHEMICAL PARAMETERS; PARALICHTHYS-OLIVACEUS; ANTIOXIDANT DEFENSE; OXIDATIVE STRESS; FRUITING BODIES; HEAT-STRESS; MUSHROOM; PERFORMANCE; FISH;

D O I：

10.1016/j.anifeedsci.2022.115342

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Functional feed additives have been promising possibilities for improving fish immune function. The present study attempts to investigate the effect of dietary Hericium erinaceus (HE) supple-mentation on growth performance, hematology, disease resistance, and expression of genes related immune response against thermal challenge in Nile tilapia. Four isonitrogenous and isolipidic diets were prepared: a control diet without HE supplementation (HE0), HE supple-mentation at 5 g/kg (HE5), 10 g/kg (HE10), and 20 g/kg (HE20). Each diet was fed to quadru-plicate groups of Nile tilapia (9.96 +/- 0.01 g/fish) to apparent satiation two times daily for 10 weeks. The dietary HE supplementation promoted protein productive value with a quadratic effect (P = 0.002) although it had no significant effect on other growth and feed utilization pa-rameters (P > 0.05). In addition, the dietary HE supplementation linearly increased red blood cell count, hematocrit, and hemoglobin content (P & LE; 0.001) and quadratically increased the contents of protein and albumin, as well as the alkaline phosphatase activity (P < 0.05). The aspartate Animal Feed Science and Technology 290 (2022) 115342 aminotransferase activity was linearly and quadratically decreased (P = 0.037, 0.017), and the plasma cortisol level was linearly decreased by increasing HE levels (P = 0.001). The microbial resistance of Nile tilapia against Streptococcus agalactiae increased in all HE-supplemented groups compared to the control group in association with the significant increases in hepatic mRNA levels of genes related immunity, including TNF-alpha, IL-1 beta, IL-6, IL-10, and TGF-beta. The dietary HE supplementation did not significantly affect the pre-thermal challenge expression of HSP70cB1 mRNAs (P > 0.05), but significantly decreased HSP70cB1 transcripts and plasma cortisol levels after thermal stress challenge (P < 0.05). Therefore, it is suggested that HE at 10 g/kg can be used as a feed additive that enhances the immunity response, reduces the risk of infectious diseases caused by S. agalactiae, and improved thermal stress resistance in Nile tilapia culture.

引用

页数：14

共 81 条

[1] Use of Green Tea, Camellia sinensis L., in Practical Diet for Growth and Protection of Nile Tilapia, Oreochromis niloticus (L.), against Aeromonas hydrophila Infection [J].