Two cases of toxic anterior segment syndrome from generic trypan blue

被引：28

作者：

Buzard, Kurt ^{[1
]}

Zhang, Jue-Rong ^{[2
]}

Thumann, Gabriella ^{[4
,5
]}

Stripecke, Renata ^{[6
]}

Sunalp, Murad ^{[3
,7
]}

机构：

[1] Univ Nevada, Las Vegas, NV 89154 USA

[2] Tulare Reg Med Ctr, Tulare, CA USA

[3] Univ Calif Berkeley, Berkeley Sch Optometry, Berkeley, CA 94720 USA

[4] Univ Cologne, Dept Vitreoretinal Surg, Cologne, Germany

[5] Univ Cologne, Dept Anat, Cologne, Germany

[6] Hannover Med Sch, Dept Hematol Hemostasis Oncol & Stem Cell Transpl, D-3000 Hannover, Germany

[7] Sunalp Laser Vis, Berkeley, CA USA

来源：

JOURNAL OF CATARACT AND REFRACTIVE SURGERY | 2010年 / 36卷 / 12期

关键词：

ENDOTHELIAL-CELL DESTRUCTION; CATARACT-SURGERY; STERILE ENDOPHTHALMITIS; BENZALKONIUM CHLORIDE; INTRAOCULAR-LENS; CAPSULE; CAPSULORHEXIS; SECONDARY; MATURE;

D O I：

10.1016/j.jcrs.2010.09.017

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

We report 2 cases of toxic anterior segment syndrome (TASS) resulting from impurities in generic trypan blue that was administered intracamerally to improve visualization of the capsule. Histology of the corneal buttons revealed foci of inflammatory response and complete loss of endothelial cells. Cell culture analysis showed that the generic trypan blue was approximately twice as toxic to the endothelium as a proprietary trypan blue. Ophthalmologists should be aware that any substance administered intraocularly can be a source of complications, and they should know the source of all material used in surgery.

引用

页码：2195 / 2199

页数：5

共 26 条

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