Improved ion optics for introduction of ions into a 9.4-T Fourier transform ion cyclotron resonance mass spectrometer

被引：11

作者：

Chen, Yu ^{[1
]}

Leach, Franklin E., III ^{[2
]}

Kaiser, Nathan K. ^{[1
]}

Dang, Xibei ^{[3
]}

Ibrahim, Yehia M. ^{[2
]}

Norheim, Randolph V. ^{[2
]}

Anderson, Gordon A. ^{[2
]}

Smith, Richard D. ^{[2
]}

Marshall, Alan G. ^{[1
,3
]}

机构：

[1] Florida State Univ, Natl High Magnet Field Lab, Ion Cyclotron Resonance Program, Tallahassee, FL 32310 USA

[2] Pacific NW Natl Lab, Richland, WA 99352 USA

[3] Florida State Univ, Dept Chem & Biochem, Tallahassee, FL 32306 USA

来源：

JOURNAL OF MASS SPECTROMETRY | 2015年 / 50卷 / 01期

基金：

美国国家科学基金会;

关键词：

FT MS; ICR; quadrupole ion guide; ion funnel; mass selection; ELECTRON-CAPTURE DISSOCIATION; FUNNEL INTERFACE; RESOLUTION; SENSITIVITY; IMPLEMENTATION; ACCUMULATION; EXCITATION; PROTEIN;

D O I：

10.1002/jms.3523

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Enhancements to the ion source and transfer optics of our 9.4T Fourier transform ion cyclotron resonance (ICR) mass spectrometer have resulted in improved ion transmission efficiency for more sensitive mass measurement of complex mixtures at the MS and MS/MS levels. The tube lens/skimmer has been replaced by a dual ion funnel and the following octopole by a quadrupole for reduced ion cloud radial expansion before transmission into a mass-selective quadrupole. The number of ions that reach the ICR cell is increased by an order of magnitude for the funnel/quadrupole relative to the tube lens/skimmer/octopole. Copyright (c) 2015 John Wiley & Sons, Ltd.

引用

页码：280 / 284

页数：5

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