Ultrasound Findings in Fetal Congenital Heart Block Associated With Maternal Anti-Ro/SSA and Anti-La/SSB Antibodies

被引：5

作者：

Lai, Jasmine ^{[1
]}

Clark, Toshi J. ^{[2
]}

Tan, Justin H. ^{[3
]}

Delaney, Shani ^{[1
]}

Jolley, Jennifer A. ^{[1
]}

机构：

[1] Univ Washington, Med Ctr, Dept Obstet & Gynecol, Div Maternal Fetal Med, Seattle, WA 98195 USA

[2] Univ Washington, Med Ctr, Dept Radiol, Div Body Imaging, Seattle, WA 98195 USA

[3] Univ Calif San Diego, San Diego Med Ctr, Dept Radiol, San Diego, CA 92103 USA

来源：

ULTRASOUND QUARTERLY | 2015年 / 31卷 / 01期

关键词：

fetal congenital heart block; neonatal lupus erythematosus; fetal bradyarrhythmia; NEONATAL LUPUS; CARDIAC MANIFESTATIONS; ATRIOVENTRICULAR-BLOCK; RECURRENCE RATES; RISK; HYDROXYCHLOROQUINE; MORBIDITY; MORTALITY; REGISTRY;

D O I：

10.1097/RUQ.0000000000000112

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

We present the sonographic features of a second-trimester fetus diagnosed with a bradyarrhythmia at 19 weeks' gestation. The mother carried a diagnosis of Sjogren syndrome, including the presence of SSA and SSB antibodies. Ultrasound M-mode and fetal echocardiogram revealed the etiology of the bradycardia to be a complete fetal congenital heart block, likely due to transplacental passage of autoimmune anti-Ro/SSA and anti-La/SSB antibodies. Consequential to the congenital heart block, the fetus developed hydrops fetalis at 21 weeks' gestational age. We discuss the 2 major etiologies of congenital heart block and the implications in subsequent pregnancies.

引用

页码：34 / 36

页数：3

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