Relationship between serum cystatin C and prognosis of nondiabetic peritoneal dialysis patients

被引：1
作者：
Zhang, Suojian [1 ]
Cao, Juan [2 ]
Zhang, Xu [2 ]
Qiao, Zhenguo [3 ]
Xie, Yan [1 ]
机构：
[1] Soochow Univ, Affiliated Hosp 1, Dept Geriatr, 899 Pinghai Rd, Suzhou 215006, Jiangsu, Peoples R China
[2] First Peoples Hosp Taixing Dist, Dept Nephrol, Taizhou, Peoples R China
[3] First Peoples Hosp Wujiang Dist, Dept Gastroenterol, Suzhou, Peoples R China
来源：
THERAPEUTIC APHERESIS AND DIALYSIS | 2020年 / 24卷 / 06期
关键词：
nondiabetic patients; peritoneal dialysis residual renal function; prognosis; serum cystatin C; RESIDUAL RENAL-FUNCTION; GLOMERULAR-FILTRATION-RATE; DIABETIC-PATIENTS; FOLLOW-UP; CREATININE; EQUATIONS; ADEQUACY; MARKER; MORTALITY; IMPACT;
D O I：
10.1111/1744-9987.13478
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We investigated whether serum cystatin C predicted treatment failure and mortality in nondiabetic peritoneal dialysis (PD) patients. We studied 163 new-onset, nondiabetic PD patients between January 2010 and January 2019. Patients were followed up until death or 1 July 2019. Serum cystatin C was measured within 1 week before PD. Basic demographic and laboratory test data were collected. Patients were divided into low (<5.54 mg/L) and high (>= 5.54 mg/L) serum cystatin C groups. The Kaplan-Meier method and log-rank test showed that the technical survival rate of the low cystatin C group was higher than that of the high cystatin C group. There was no difference in overall survival between the two groups. Multivariate Cox model showed that serum cystatin C was an independent risk factor for PD failure. Serum cystatin C could predict PD failure but was not associated with mortality in nondiabetic PD patients.
引用
收藏
页码：703 / 708
页数：6
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