Evaluation of NovoRapid infusion as a treatment option in the management of diabetic ketoacidosis

被引：1

作者：

Kwok, Raylene ^{[1
]}

Sztal-Mazer, Shoshana ^{[2
]}

Hopkins, Ria E. ^{[1
]}

Poole, Susan G. ^{[1
,3
]}

Grannell, Louise ^{[1
]}

Coutsouvelis, John ^{[1
,3
]}

Topliss, Duncan J. ^{[2
,4
]}

机构：

[1] Alfred Hlth, Pharm Dept, 55 Commercial Rd, Melbourne, Vic 3004, Australia

[2] Alfred Hlth, Dept Endocrinol & Diabet, Melbourne, Vic, Australia

[3] Monash Univ, Ctr Med Use & Safety, Fac Pharm & Pharmaceut Sci, Melbourne, Vic, Australia

[4] Monash Univ, Dept Med, Fac Med Nursing & Hlth Sci, Melbourne, Vic, Australia

来源：

INTERNAL MEDICINE JOURNAL | 2017年 / 47卷 / 11期

关键词：

diabetic ketoacidosis; insulin; insulin aspart; infusions; intravenous; short acting; HYPERGLYCEMIC EMERGENCIES; INSULIN ASPART;

D O I：

10.1111/imj.13607

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This study evaluates the clinical efficacy and safety of NovoRapid (insulin aspart) compared to Actrapid (human neutral insulin) for diabetic ketoacidosis (DKA). In this retrospective study involving 40 patients, no statistically significant differences were observed between biochemical variables, infusion duration or complications in patients treated with insulin aspart or human neutral insulin. These results support the use of insulin aspart as an effective and safe alternative to human neutral insulin in DKA.

引用

页码：1317 / 1320

页数：4

共 10 条

[1]

[Anonymous], DIABETES MANAG

[2] Current Diagnosis and Treatment of Hyperglycemic Emergencies [J].

Corwell, Brian ;

Knight, Brandi ;

Olivieri, Laura ;

Willis, George C. .

EMERGENCY MEDICINE CLINICS OF NORTH AMERICA, 2014, 32 (02) :437-+

[3]

Frier BM, 2000, DIABETES-METAB RES, V16, P262, DOI 10.1002/1520-7560(2000)9999:9999<::AID-DMRR120>3.3.CO

[4]

2-T

[5] Management of hyperglycemic crises in patients with diabetes [J].

Kitabchi, AE ;

Umpierrez, GE ;

Murphy, MB ;

Barrett, EJ ;

Kreisberg, RA ;

Malone, JI ;

Wall, BM .

DIABETES CARE, 2001, 24 (01) :131-153

[6]

Novo Nordisk, 2014, PRODUCT INFORM INSUL

[7]

Novo Nordisk, 2012, PRODUCT INFORM HUMAN

[8] Evidence-based management of hyperglycemic emergencies in diabetes mellitus [J].

Nyenwe, Ebenezer A. ;

Kitabchi, Abbas E. .

DIABETES RESEARCH AND CLINICAL PRACTICE, 2011, 94 (03) :340-351

[9] Comparative effect of human soluble insulin and insulin aspart upon hypoglycaemia-induced alterations in cardiac repolarization [J].

Robinson, RTCE ;

Harris, ND ;

Ireland, RH ;

Lindholm, A ;

Heller, SR .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2003, 55 (03) :246-251

[10] Insulin Analogs Versus Human Insulin in the Treatment of Patients With Diabetic Ketoacidosis A randomized controlled trial [J].

Umpierrez, Guillermo E. ;

Jones, Sidney ;

Smiley, Dawn ;

Mulligan, Patrick ;

Keyler, Trevor ;

Temponi, Angel ;

Semakula, Crispin ;

Umpierrez, Denise ;

Peng, Limin ;

Ceron, Miguel ;

Robalino, Gonzalo .

DIABETES CARE, 2009, 32 (07) :1164-1169

← 1 →