[18F]-NaF PET/CT imaging in cardiac amyloidosis

被引：46

作者：

Van der Gucht, Axel ^{[1
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]}

Galat, Arnault ^{[1
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]}

Rosso, Jean ^{[1
,2
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]}

Guellich, Aziz ^{[1
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,3
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]}

Garot, Jerome ^{[7
]}

Bodez, Diane ^{[1
,2
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]}

Plante-Bordeneuve, Violaine ^{[1
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,8
]}

Hittinger, Luc ^{[1
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]}

Dubois-Rande, Jean-Luc ^{[1
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]}

Evangelista, Eva ^{[1
,3
,4
]}

Sasanelli, Myriam ^{[1
,3
,4
]}

Chalaye, Julia ^{[1
,3
,4
]}

Meignan, Michel ^{[1
,2
,3
,4
]}

Itti, Emmanuel ^{[1
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]}

Damy, Thibaud ^{[1
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]}

机构：

[1] UPEC, Henri Mondor Teaching Hosp, AP HP, Creteil, France

[2] Mondor Amyloidosis Network, Creteil, France

[3] DHU ATVB, Creteil, France

[4] Henri Mondor Teaching Hosp, AP HP, Dept Nucl Med, 51 Ave Mal Lattre Tassigny, F-94010 Creteil, France

[5] GRC Reseau Amylose Mondor, INSERM, U955, Creteil, France

[6] Henri Mondor Teaching Hosp, AP HP, Dept Cardiol, Creteil, France

[7] Ramsay Generale Sante, Hop Prive Jacques Cartier, Dept Inst Cardiovasc Paris Sud, Cardiovasc Magnet Resonance Dept, Massy, France

[8] Henri Mondor Teaching Hosp, AP HP, Dept Neurol, Creteil, France

来源：

JOURNAL OF NUCLEAR CARDIOLOGY | 2016年 / 23卷 / 04期

关键词：

PET/CT; 18F]-NaF; cardiac amyloidosis; protein deposition; SCINTIGRAPHY; DIAGNOSIS;

D O I：

10.1007/s12350-015-0287-0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cardiac amyloidosis (CA) is recognized as a common cause of restrictive cardiomyopathy and heart failure due to the deposition of insoluble proteins in the myocardial interstitium. We emphasize the role of [18F]-sodium fluoride (NaF) PET/CT as a potential noninvasive tool to identify and differentiate the transthyretin-related cardiac amyloidosis from the light-chain cardiac amyloidosis. We report cases of a 73-year-old man and a 75-year-old woman followed in our center for congestive heart failure with marked alteration of the left ventricular ejection fraction due to familial transthyretin Val122Ile cardiac amyloidosis and light-chain cardiac amyloidosis, respectively, confirmed on endomyocardial biopsy.

引用

页码：846 / 849

页数：4

共 5 条

[1]

Galat A, 2015, AMYLOID IN PRESS

[2] Bone scintigraphy with 99mtechnetium-hydroxymethylene diphosphonate allows early diagnosis of cardiac involvement in patients with transthyretin-derived systemic amyloidosis [J].

Glaudemans, Andor W. J. M. ;

van Rheenen, Ronald W. J. ;

van den Berg, Maarten P. ;

Noordzij, Walter ;

Koole, Michel ;

Blokzijl, Hans ;

Dierckx, Rudi A. J. O. ;

Slart, Riemer H. J. A. ;

Hazenberg, Bouke P. C. .

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 2014, 21 (01) :35-44

[3] Uptake of technetium 99m HDP in cardiac amyloidosis [J].

Kulhanek, J ;

Movahed, A .

INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING, 2003, 19 (03) :225-227

[4] Role of 99mTc-DPD Scintigraphy in Diagnosis and Prognosis of Hereditary Transthyretin-Related Cardiac Amyloidosis [J].

Rapezzi, Claudio ;

Quarta, Candida C. ;

Guidalotti, Pier Luigi ;

Pettinato, Cinzia ;

Fanti, Stefano ;

Leone, Ornella ;

Ferlini, Alessandra ;

Longhi, Simone ;

Lorenzini, Massimiliano ;

Reggiani, Letizia Bacchi ;

Gagliardi, Christian ;

Gallo, Pamela ;

Villani, Caterina ;

Salvi, Fabrizio .

JACC-CARDIOVASCULAR IMAGING, 2011, 4 (06) :659-670

[5]

WORSLEY DF, 1993, J NUCL MED, V34, P1612

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