Machine Learning for Real-Time Heart Disease Prediction

被引:37
作者
Bertsimas, Dimitris [1 ]
Mingardi, Luca [2 ]
Stellato, Bartolomeo [3 ]
机构
[1] MIT, Sloan Sch Management, 77 Massachusetts Ave, Cambridge, MA 02139 USA
[2] MIT, Operat Res Ctr, 77 Massachusetts Ave, Cambridge, MA 02139 USA
[3] Princeton Univ, Dept Operat Res & Financial Engn, Princeton, NJ 08540 USA
关键词
Feature extraction; Electrocardiography; Heart; Diseases; Real-time systems; Data models; Time series analysis; Arrhythmia; boosting; ECG; machine learning;
D O I
10.1109/JBHI.2021.3066347
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
Heart-related anomalies are among the most common causes of death worldwide. Patients are often asymptomatic until a fatal event happens, and even when they are under observation, trained personnel is needed in order to identify a heart anomaly. In the last decades, there has been increasing evidence of how Machine Learning can be leveraged to detect such anomalies, thanks to the availability of Electrocardiograms (ECG) in digital format. New developments in technology have allowed to exploit such data to build models able to analyze the patterns in the occurrence of heart beats, and spot anomalies from them. In this work, we propose a novel methodology to extract ECG-related features and predict the type of ECG recorded in real time (less than 30 milliseconds). Our models leverage a collection of almost 40 thousand ECGs labeled by expert cardiologists across different hospitals and countries, and are able to detect 7 types of signals: Normal, AF, Tachycardia, Bradycardia, Arrhythmia, Other or Noisy. We exploit the XGBoost algorithm, a leading machine learning method, to train models achieving out of sample F1 Scores in the range 0.93 - 0.99. To our knowledge, this is the first work reporting high performance across hospitals, countries and recording standards.
引用
收藏
页码:3627 / 3637
页数:11
相关论文
共 33 条
[1]   Optuna: A Next-generation Hyperparameter Optimization Framework [J].
Akiba, Takuya ;
Sano, Shotaro ;
Yanase, Toshihiko ;
Ohta, Takeru ;
Koyama, Masanori .
KDD'19: PROCEEDINGS OF THE 25TH ACM SIGKDD INTERNATIONAL CONFERENCCE ON KNOWLEDGE DISCOVERY AND DATA MINING, 2019, :2623-2631
[2]  
Alivecor Inc., 2020, AL COM
[3]  
[Anonymous], 2019, TIANCHI ECG ABNORMAL
[4]  
Ary Z. D. G., 2017, SCIENCEDIRECT COM GO
[5]   An artificial intelligence-enabled ECG algorithm for the identification of patients with atrial fibrillation during sinus rhythm: a retrospective analysis of outcome prediction [J].
Attia, Zachi, I ;
Noseworthy, Peter A. ;
Lopez-Jimenez, Francisco ;
Asirvatham, Samuel J. ;
Deshmukh, Abhishek J. ;
Gersh, Bernard J. ;
Carter, Rickey E. ;
Yao, Xiaoxi ;
Rabinstein, Alejandro A. ;
Erickson, Brad J. ;
Kapa, Suraj ;
Friedman, Paul A. .
LANCET, 2019, 394 (10201) :861-867
[6]  
Butterworth S., 1930, EXPT WIRELESS WIRELE, V7, P536
[7]  
C. for Disease Control and Prevention, 2020, ATRIAL FIBRILLATION
[8]  
C. for Disease Control and Prevention, 2017, DEATHS MORTALITY
[9]   Multi-ECGNet for ECG Arrythmia Multi-Label Classification [J].
Cai, Junxian ;
Sun, Weiwei ;
Guan, Jianfeng ;
You, Ilsun .
IEEE ACCESS, 2020, 8 :110848-110858
[10]  
Campbell GA, 1922, BELL SYST TECH J, V1, P1