hypeR: an R package for geneset enrichment workflows

被引：99

作者：

Federico, Anthony ^{[1
,2
]}

Monti, Stefano ^{[1
,2
]}

机构：

[1] Boston Univ, Bioinformat Dept, Boston, MA 02118 USA

[2] Boston Univ, Sect Computat Biomed, Sch Med, Boston, MA 02118 USA

来源：

BIOINFORMATICS | 2020年 / 36卷 / 04期

关键词：

D O I：

10.1093/bioinformatics/btz700

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A Summary: Geneset enrichment is a popular method for annotating high-throughput sequencing data. Existing tools fall short in providing the flexibility to tackle the varied challenges researchers face in such analyses, particularly when analyzing many signatures across multiple experiments. We present a comprehensive R package for geneset enrichment workflows that offers multiple enrichment, visualization, and sharing methods in addition to novel features such as hierarchical geneset analysis and built-in markdown reporting. hypeR is a one-stop solution to performing geneset enrichment for a wide audience and range of use cases.

引用

页码：1307 / 1308

页数：2

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