Indocyanine green fluorescence-guided surgery after IV injection in metastatic colorectal cancer: A systematic review

被引：85

作者：

Liberale, G. ^{[1
]}

Bourgeois, P. ^{[2
,3
]}

Larsimont, D. ^{[4
]}

Moreau, M. ^{[5
]}

Donckier, V. ^{[1
]}

Ishizawa, T. ^{[6
]}

机构：

[1] Dept Surg Oncol, Brussels, Belgium

[2] Univ Libre Bruxelles, Inst Jules Bordet, Dept Nucl Med, Brussels, Belgium

[3] Univ Libre Bruxelles, Inst Jules Bordet, Clin Unit Lymphol, R&D Grp Clin Applicat Fluorescence Imaging, Brussels, Belgium

[4] Dept Pathol, Brussels, Belgium

[5] Dept Stat, Brussels, Belgium

[6] Univ Tokyo, Grad Sch Med, Hepatobiliaty Pancreat Surg Div, Dept Surg, Tokyo, Japan

来源：

EJSO | 2017年 / 43卷 / 09期

关键词：

Review; Lymph node metastases; Peritoneal carcinomatosis; Hepatic metastases; Indocyanine green; Colorectal cancer; INTRAOPERATIVE INTRAVENOUS-INJECTION; LYMPH-NODE METASTASES; PERITONEAL CARCINOMATOSIS; SURGICAL-MANAGEMENT; HEPATIC RESECTION; LIVER METASTASES; INTRAPERITONEAL CHEMOTHERAPY; LAPAROSCOPIC CHOLECYSTECTOMY; RETROPERITONEAL RECURRENCES; CYTOREDUCTIVE SURGERY;

D O I：

10.1016/j.ejso.2017.04.015

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Objective: Indocyanine green fluorescence-guided surgery (ICG-FGS) has emerged as a potential new imaging modality for improving the detection of hepatic,. ymph node (LN), and peritoneal metastases in colorectal cancer (CRC) patients. The aim of this paper is to review the available literature in the clinical setting of ICG-FGS for tumoral detection in various fields of metastatic colorectal disease. Methods: PubMed and Medline literature databases were searched for original articles on the use of ICG in the setting of clinical studies on colorectal cancer. The search terms used were "near-infrared fluorescence", "intraoperative imaging", "indocyanine green", "human" and "colorectal cancer". Results: ICG fluorescence imaging (ICG-FI) is clearly supported as an intraoperative technique that allows the detection of additional superficial hepatic metastases of CRC. Data on the role of ICG-FI in the intraoperative detection of peritoneal metastases and LN metastases are scarce but encouraging and ICG-FI could potentially improve the staging and treatment of these patients. Conclusion: ICG-FI is a promising imaging technique in the detection of small infraclinic LN, hepatic, and peritoneal metastatic deposits that may allow better staging and more complete surgical resection with a potential prognostic benefit for patients. (C) 2017 Elsevier Ltd, BASO- The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.

引用

页码：1656 / 1667

页数：12

共 97 条

[91] Near-Infrared Fluorescence Imaging of Liver Metastases in Rats using Indocyanine Green [J].