Biocompatibility of modified silica-protein composite layers

被引：42
作者：
Brasack, I
Böttcher, H
Hempel, U
机构：
[1] Feinchem GmbH Sebnitz, D-01855 Sebnitz, Germany
[2] TU Dresden, Inst Physiol Chem, D-01109 Dresden, Germany
来源：
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY | 2000年 / 19卷 / 1-3期
关键词：
biocomposite layers; silica; gelatine; biocompatibility;
D O I：
10.1023/A:1008763900729
中图分类号：
TQ174 [陶瓷工业]; TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Biocomposite layers of silica and various bone-relevant proteins such as collagen, gelatine and commercial collagen hydrolysate can be obtained from coatings of silica sols mixed with proteins in water/dioxane. Investigations into the mechanical and cell proliferation properties for different sol parameters (pH, solvent), type and concentration of proteins, annealing and crosslinking of the biocomposite layers revealed that such coatings are highly biocompatible with excellent mechanical properties.
引用
收藏
页码：479 / 482
页数：4
相关论文
共 16 条
  • [1] Addadi L., 1992, ANGEW CHEM, V104, P159
  • [2] [Anonymous], 1992, 10993 ISO 5
  • [3] ENZYMES AND OTHER PROTEINS ENTRAPPED IN SOL-GEL MATERIALS
    AVNIR, D
    BRAUN, S
    LEV, O
    OTTOLENGHI, M
    [J]. CHEMISTRY OF MATERIALS, 1994, 6 (10) : 1605 - 1614
  • [4] SOL-GEL ENCAPSULATION METHODS FOR BIOSENSORS
    DAVE, BC
    DUNN, B
    VALENTINE, JS
    ZINK, JI
    [J]. ANALYTICAL CHEMISTRY, 1994, 66 (22) : A1120 - A1127
  • [5] Strategies for encapsulating biomolecules in sol-gel matrices
    Dunn, B
    Miller, JM
    Dave, BC
    Valentine, JS
    Zink, JI
    [J]. ACTA MATERIALIA, 1998, 46 (03) : 737 - 741
  • [6] Molecular control of bioactivity in sol-gel glasses
    Hench, LL
    Wheeler, DL
    Greenspan, DC
    [J]. JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY, 1998, 13 (1-3) : 245 - 250
  • [7] Sol-gel materials for bioceramic applications
    Hench, LL
    [J]. CURRENT OPINION IN SOLID STATE & MATERIALS SCIENCE, 1997, 2 (05) : 604 - 610
  • [8] Interfacial aspects of biomineralization
    Hunter, GK
    [J]. CURRENT OPINION IN SOLID STATE & MATERIALS SCIENCE, 1996, 1 (03) : 430 - 435
  • [9] IN-VIVO CALCIUM-PHOSPHATE FORMATION INDUCED BY SOL-GEL-PREPARED SILICA
    LI, PJ
    YE, X
    KANGASNIEMI, I
    DEBLIECKHOGERVORST, JMA
    KLEIN, CPAT
    DEGROOT, K
    [J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1995, 29 (03): : 325 - 328
  • [10] APATITE FORMATION INDUCED BY SILICA-GEL IN A SIMULATED BODY-FLUID
    LI, PJ
    OHTSUKI, C
    KOKUBO, T
    NAKANISHI, K
    SOGA, N
    NAKAMURA, T
    YAMAMURO, T
    [J]. JOURNAL OF THE AMERICAN CERAMIC SOCIETY, 1992, 75 (08) : 2094 - 2097
12