Synthesis and reactivity of 2,3-dihydro-1H-2,3-benzodiazepine-1,4(5H)-dione

被引：7
作者：
Bihel, Frederic J. -J. [1 ]
Hellal, Malik [1 ]
Bourguignon, Jean-Jacques [1 ]
机构：
[1] Univ Strasbourg 1, CNRS, Fac Pharm,Inst Gilbert Laustriat, Dept Pharmacochim Commun Cellulaire,UMR 7175, F-67400 Illkirch Graffenstaden, France
来源：
SYNTHESIS-STUTTGART | 2007年 / 24期
关键词：
benzodiazepine; hydrazine; amides; aminations; bicyclic compounds;
D O I：
10.1055/s-2007-990893
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Based on an orthogonal protective group strategy dealing with N-protected hydrazine, we established for the first time a highly efficient synthetic pathway leading to 2,3-benzodiazepine-1,4-dione. Moreover, the versatile reactivities exhibited by this 2,3-benzodiazepine-1,4-dione were evaluated towards both benzylation and amination reactions.
引用
收藏
页码：3791 / 3796
页数：6
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