PROTEOMICS TECHNOLOGIES FOR THE GLOBAL IDENTIFICATION AND QUANTIFICATION OF PROTEINS

被引：0
|
作者：
Brewis, Ian A. [1 ,2 ]
Brennan, P. [1 ]
机构：
[1] Cardiff Univ, Sch Med, Dept Infect Immun & Biochem, Cardiff, S Glam, Wales
[2] Cardiff Univ, Sch Med, Cent Biotechnol Serv, Cardiff, S Glam, Wales
来源：
ADVANCES IN PROTEIN CHEMISTRY AND STRUCTURAL BIOLOGY | 2010年 / 80卷
关键词：
DIFFERENCE GEL-ELECTROPHORESIS; SPECTROMETRY-BASED PROTEOMICS; MASS-SPECTROMETRY; QUANTITATIVE PROTEOMICS; POSTTRANSLATIONAL MODIFICATIONS; 2-DIMENSIONAL ELECTROPHORESIS; SUBCELLULAR-LOCALIZATION; ABSOLUTE QUANTIFICATION; EUKARYOTIC PROTEOME; EXPERIMENTAL-DESIGN;
D O I：
10.1016/S1876-1623(10)80001-X
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
This review provides an introduction for the nonspecialist to proteomics and in particular the major approaches available for global protein identification and quantification. Proteomics technologies offer considerable opportunities for improved biological understanding and biomarker discovery. The central platform for proteomics is tandem mass spectrometry (MS) but a number of other technologies, resources, and expertise are
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页码：1 / 44
页数：44
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