Catalytic Characteristics of NADP-Isocitrate Dehydrogenase from the Liver of Rats in Health and after Injection of TNF-α and Melatonin Treatment

被引：0

作者：

Tsvetikova, L. N. ^{[1
]}

Popova, T. N. ^{[1
]}

Rakhmanova, T. I. ^{[1
]}

机构：

[1] Voronezh State Univ, Voronezh, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2011年 / 150卷 / 03期

关键词：

rat; liver; apoptosis; NADP-dependent isocitrate dehydrogenase; melatonin; APOPTOSIS;

D O I：

10.1007/s10517-011-1129-y

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Activity of NADP-dependent isocitrate dehydrogenase (EC 1.1.1.42) increases and the catalytic characteristics of the enzyme isolated from the liver of rats are changed under conditions of apoptosis induction in comparison with these characteristics in health. Injection of melatonin induced a trend to normalization of kinetic parameters of catalytic activity and of some regulatory characteristics of the enzyme.

引用

页码：307 / 310

页数：4

共 6 条

[1] Catalytic Characteristics of NADP-Isocitrate Dehydrogenase from the Liver of Rats in Health and after Injection of TNF-α and Melatonin Treatment
L. N. Tsvetikova
T. N. Popova
T. I. Rakhmanova
Bulletin of Experimental Biology and Medicine, 2011, 150 : 307 - 310
[2] CATALYTIC PROPERTIES OF NADP-ISOCITRATE DEHYDROGENASE FROM THE MAIZE SCUTELLUM
POPOVA, TN
IZVESTIYA AKADEMII NAUK SERIYA BIOLOGICHESKAYA, 1993, (05): : 652 - 659
[3] Expression and catalytic properties of rat liver NADP-isocitrate dehydrogenase under normal conditions, after administration of tumor necrosis factor-α and thioctic acid action
Tsvetikova L.N.
Popova T.N.
Rakhmanova T.I.
Iskusnykh I.Y.
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry, 2010, 4 (2) : 191 - 197
[4] NADP-LINKED ISOCITRATE DEHYDROGENASE FROM BEEF LIVER - PURIFICATION, QUATERNARY STRUCTURE AND CATALYTIC ACTIVITY
CARLIER, MF
PANTALONI, D
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1973, 37 (02): : 341 - 354
[5] A STUDY OF THE BIOCHEMICAL CHARACTERISTICS OF NADP+ ISOCITRATE DEHYDROGENASE FROM THE LIVER AND KIDNEY OF THE ARABIAN CAMEL (CAMELUS-DROMEDARIUS)
ALALI, AK
ALHUSAYNI, H
ALMUTAIRY, A
SABA, R
POWER, DM
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 1989, 92 (03): : 517 - 521
[6] DETERMINATION OF CATALYTIC ACTIVITY AND ALLOSTERIC PROPERTIES OF GLUTAMATE DEHYDROGENASE AFTER THE THERMAL TREATMENT OF LIVER TISSUES TAKEN FROM 2 FROG SPECIES
YAKOVLEV.VI
GUBNITSK.LS
TSITOLOGIYA, 1972, 14 (06): : 721 - &

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