ATM and ATR are not required for DNA damage-dependent accumulation of Chk1 at the centrosome.

被引:0
作者
Loeffler, H
Bochtler, T
Ho, AD
Jeggo, PA
Bartek, J
Kraemer, A
机构
[1] Univ Heidelberg, Med Klin, Abt Innere Med 5, Heidelberg, Germany
[2] Univ Sussex, Genome Damage & Stabil Ctr, Brighton, E Sussex, England
[3] Danish Canc Soc, Dept Cell Cycle & Canc, Copenhagen, Denmark
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
4288
引用
收藏
页码:152B / 152B
页数:1
相关论文
共 50 条
  • [31] An overactivated ATR/CHK1 pathway is responsible for the prolonged G2 accumulation in irradiated AT cells
    Wang, X
    Khadpe, J
    Hu, BC
    Iliakis, G
    Wang, Y
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (33) : 30869 - 30874
  • [32] Genetic analysis of CHK1 and CHK2 homologues revealed a unique cross talk between ATM and ATR pathways in Neurospora crassa
    Wakabayashi, Michiyoshi
    Ishii, Chizu
    Inoue, Hirokazu
    Tanaka, Shuuitsu
    DNA REPAIR, 2008, 7 (12) : 1951 - 1961
  • [33] Cdk-mediated phosphorylation of Chk1 is required for efficient activation and full checkpoint proficiency in response to DNA damage
    Xu, N.
    Libertini, S.
    Black, E. J.
    Lao, Y.
    Hegarat, N.
    Walker, M.
    Gillespie, D. A.
    ONCOGENE, 2012, 31 (09) : 1086 - 1094
  • [34] Cdk-mediated phosphorylation of Chk1 is required for efficient activation and full checkpoint proficiency in response to DNA damage
    N Xu
    S Libertini
    E J Black
    Y Lao
    N Hegarat
    M Walker
    D A Gillespie
    Oncogene, 2012, 31 : 1086 - 1094
  • [35] Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage
    Syljuåsen, RG
    Sorensen, CS
    Hansen, LT
    Fugger, K
    Lundin, C
    Johansson, F
    Helleday, T
    Sehested, M
    Lukas, J
    Bartek, J
    MOLECULAR AND CELLULAR BIOLOGY, 2005, 25 (09) : 3553 - 3562
  • [36] ATM/Chk2 and ATR/Chk1 Pathways Respond to DNA Damage Induced by Movento® 240SC and Envidor® 240SC Keto-Enol Insecticides in the Germarium of Drosophila melanogaster
    Gonzalez-Marin, Berenyce
    Calderon-Segura, Maria Elena
    Sekelsky, Jeff
    TOXICS, 2023, 11 (09)
  • [37] From checkpoint to checkpoint: DNA damage ATR/Chk1 checkpoint signalling elicits PD-L1 immune checkpoint activation
    Mouw, Kent W.
    Konstantinopoulos, Panagiotis A.
    BRITISH JOURNAL OF CANCER, 2018, 118 (07) : 933 - 935
  • [38] Cell cycle-dependent DNA damage signaling induced by ICRF-193 involves ATM, ATR, CHK2, and BRCA1
    Park, Iha
    Avraham, Hava Karsenty
    EXPERIMENTAL CELL RESEARCH, 2006, 312 (11) : 1996 - 2008
  • [39] Therapeutic targeting of the DNA damage mediators CHK1 and Wee1 in neuroblastoma
    Russell, Mike
    Levin, Kirill
    Rader, JulieAnn
    Toniatti, Carlo
    Maris, John M.
    Cole, Kristina A.
    CANCER RESEARCH, 2012, 72
  • [40] ATR, claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage
    Sorensen, CS
    Syljuåsen, RG
    Lukas, J
    Bartek, J
    CELL CYCLE, 2004, 3 (07) : 941 - 945