Capecitabine in pretreated metastatic cholangiocarcinoma. A case report and review of the literature

被引:0
作者
Koutras, A. K. [1 ]
Talampuka, G. [1 ]
Pagoni, N. [2 ]
Thomopoulos, K. C. [2 ]
Kalliolias, G. [1 ]
Kalogeropoulou, C. [3 ]
Kalofonos, H. P. [1 ]
机构
[1] Univ Hosp, Patras Med Sch, Dept Med, Div Oncol, Rion 26504, Greece
[2] Univ Hosp, Patras Med Sch, Dept Med, Div Gastroenterol, Rion 26504, Greece
[3] Univ Hosp, Patras Med Sch, Dept Radiol, Rion 26504, Greece
来源
JOURNAL OF BUON | 2007年 / 12卷 / 02期
关键词
capecitabine; cholangiocarcinoma; metastatic; pretreated;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Cholangiocarcinoma is one of the most aggressive malignancies. Patients with advanced or metastatic disease have a particularly dismal prognosis. The role of chemotherapy remains a matter of debate. A number of recent trials have shown that capecitabine in combination with other agents seems to be active as first-line treatment in advanced biliary cancer. Clinical data regarding the activity of capecitabine in pretreated patients are limited. metastatic cholangiocarcinoma who developed stabilization of the disease for 7 months following chemotherapy with capecitabine. The patient had previously received 2 lines of chemotherapy. Capecitabine was tolerated fairly well without serious adverse events. We consider this observation to be important given the absence of active, non-surgical treatments in unresectable tumors.
引用
收藏
页码:281 / 283
页数:3
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