Two Erythrina alkaloids and three diarylpropanoids from Erythrina velutina

被引：4

作者：

Todoroki, Kazuyuki ^{[1
]}

Funasaki, Mariko ^{[1
]}

Etoh, Tadahiro ^{[2
]}

Matsuzaki, Keiichi ^{[3
]}

Ohsaki, Ayumi ^{[1
]}

机构：

[1] Nihon Univ, Coll Humanities & Sci, Setagaya Ku, Tokyo 1568550, Japan

[2] Iryo Sosei Univ, Dept Pharm, Iwaki, Fukushima 9708551, Japan

[3] Nihon Univ, Sch Pharm, 7-7-1 Narashinodai, Funabashi, Chiba 2748555, Japan

来源：

TETRAHEDRON | 2021年 / 96卷

关键词：

Erythrina alkaloids; Diarylpropanoids; Erythrina velutina; Nitric oxide production inhibitory effect; Cytotoxic activity; HeLa and HL-60 cell lines;

D O I：

10.1016/j.tet.2021.132383

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two new Erythrina alkaloid glycosides, 1 and 2, and three new diarylpropanoid glycosides 12-14 together with nine known compounds were isolated from the MeOH extracts of the seeds of Erythrina velutina. The structures and absolute configurations of these new compounds were elucidated through comprehensive spectroscopic analyses as well as experimental and calculated ECD data. The inhibitory potency of these compounds against nitric oxide production in LPS-induced RAW 264.7 cells and the cytotoxicity of these compounds against the HeLa and HL-60 human cancer cell lines were also discussed. (c) 2021 Elsevier Ltd. All rights reserved.

引用

页数：7

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