Chemical Structures and Biological Activities of Limonoids from the Genus Swietenia (Meliaceae)

被引：27

作者：

Sun, Yun-Peng ^{[1
]}

Jin, Wen-Fang ^{[1
]}

Wang, Yong-Yue ^{[1
]}

Wang, Gang ^{[1
,2
]}

Morris-Natschke, Susan L. ^{[3
]}

Liu, Jin-Song ^{[1
,2
]}

Wang, Guo-Kai ^{[1
,2
,3
]}

Lee, Kuo-Hsiung ^{[3
,4
]}

机构：

[1] Anhui Univ Chinese Med, Sch Pharm, Hefei 230012, Anhui, Peoples R China

[2] Synerget Innovat Ctr Anhui Authent Chinese Med Qu, Hefei 230012, Anhui, Peoples R China

[3] Univ N Carolina, Eshelman Sch Pharm, Nat Prod Res Labs, Chapel Hill, NC 27599 USA

[4] China Med Univ & Hosp, Chinese Med Res & Dev Ctr, Taichung 40402, Taiwan

来源：

MOLECULES | 2018年 / 23卷 / 07期

基金：

中国国家自然科学基金;

关键词：

genus Swietenia; limonoids; chemical components; biological activities; PLATELET-ACTIVATING-FACTOR; MAHOGANI L JACQ; MACROPHYLLA KING; MAHAGONI JACQ; DIABETIC-RATS; ANTIMICROBIAL ACTIVITY; ANTIFEEDANT ACTIVITIES; TRADITIONAL MEDICINE; CYTOTOXIC ACTIVITIES; ANTIFUNGAL ACTIVITY;

D O I：

10.3390/molecules23071588

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Swietenia is a genus in the plant family Meliaceae. This genus contains seven to eight known species, found in the tropical and subtropical regions of the Americas and West Africa. Thus far, more than 160 limonoids have been isolated from four species of the genus Swietenia. Limonoids are rich in structure type and biological activity, and these compounds are the main active components in the Swietenia species. This paper will give a comprehensive overview of the recent phytochemical and pharmacological research on the terpenes from Swietenia plants and encourage further drug discovery research.

引用

页数：17

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