Imaging manifestations of progressive multifocal leukoencephalopathy

被引：94

作者：

Shah, R. ^{[1
]}

Bag, A. K. ^{[1
]}

Chapman, P. R. ^{[1
]}

Cure, J. K. ^{[1
]}

机构：

[1] Univ Alabama Birmingham, Dept Diagnost Radiol, Div Neuroradiol, Birmingham, AL USA

来源：

CLINICAL RADIOLOGY | 2010年 / 65卷 / 06期

关键词：

JC VIRUS-DNA; FOCAL BRAIN-LESIONS; CEREBROSPINAL-FLUID; CIDOFOVIR THERAPY; AIDS; MR; PATIENT; PML; DIAGNOSIS; SPECTROSCOPY;

D O I：

10.1016/j.crad.2010.03.001

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease caused by reactivation of JC virus in immunosuppressed patients. The diagnosis is usually suggested on imaging and confirmed by cerebrospinal fluid polymerase chain reaction (PCR) for JC virus DNA. In this article, we review the imaging manifestations of PML on computed tomography (CT), magnetic resonance imaging (MRI), diffusion-weighted imaging (DWI), diffusion tensor imaging (DTI), MR spectroscopy, single photon-emission computed tomography (SPECT) and positron-emission tomography (PET), and outline the role of imaging in follow-up and prognostication. (c) 2010 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

引用

页码：431 / 439

页数：9

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