Stem cell regenerative potential for plastic and reconstructive surgery

被引:3
作者
Bohac, Martin [1 ,2 ]
Csobonyeiova, Maria [3 ]
Kupcova, Ida [4 ,5 ]
Zamborsky, Radoslav [6 ,7 ]
Fedele, Jozef [1 ,2 ]
Koller, Jan [5 ,8 ]
机构
[1] Comenius Univ, Dept Plast Reconstruct & Aesthet Surg, Fac Med, Pazitkova 4, Bratislava 82606, Slovakia
[2] Univ Hosp, Pazitkova 4, Bratislava 82606, Slovakia
[3] Comenius Univ, Fac Med, Inst Histol & Embryol, Bratislava, Slovakia
[4] Comenius Univ, Dept Oromaxillofacial Surg, Fac Med, Bratislava, Slovakia
[5] Univ Hosp, Bratislava, Slovakia
[6] Comenius Univ, Dept Orthopaed, Fac Med, Bratislava, Slovakia
[7] Childrens Univ Hosp, Bratislava, Slovakia
[8] Comenius Univ, Dept Burn Surg & Reconstruct Surg, Fac Med, Bratislava, Slovakia
关键词
Stem cells; iPSCs; Regenerative medicine; Plastic surgery; SOFT-TISSUE AUGMENTATION; BREAST-CANCER CELLS; SPINAL-CORD-INJURY; BONE REGENERATION; ASSISTED LIPOTRANSFER; AUTOLOGOUS FAT; SUPPORTIVE USE; TENDON REPAIR; TRANSPLANTATION; THERAPY;
D O I
10.1007/s10561-016-9583-4
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Stem cells represent heterogeneous population of undifferentiated cells with unique characteristics of long term self renewal and plasticity. Moreover, they are capable of active migration to diseased tissues, secretion of different bioactive molecules, and they have immunosuppressive potential as well. They occur in all tissues through life and are involved in process of embryogenesis and regeneration. During last decades stem cells attracted significant attention in each field of medicine, including plastic and reconstructive surgery. The main goal of the present review article is to present and discuss the potential of stem cells and to provide information about their safe utilization in chronic wounds and fistulae healing, scar management, breast reconstruction, as well as in bone, tendon and peripheral nerve regeneration.
引用
收藏
页码:735 / 744
页数:10
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