Season of birth and anorexia nervosa

被引：17

作者：

Disanto, Giulio ^{[1
]}

Handel, Adam E. ^{[1
]}

Para, Andrea E. ^{[1
]}

Ramagopalan, Sreeram V. ^{[2
,3
]}

Handunnetthi, Lahiru ^{[1
]}

机构：

[1] Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England

[2] Queen Mary Univ London, Barts & London Sch Med & Dent, Blizard Inst Cell & Mol Sci, London, England

[3] Univ Oxford, Wellcome Trust Ctr Human Genet, Dept Clin Neurol, John Radcliffe Hosp, Oxford OX3 7BN, England

来源：

BRITISH JOURNAL OF PSYCHIATRY | 2011年 / 198卷 / 05期

基金：

英国惠康基金;

关键词：

EATING-DISORDERS; SCHIZOPHRENIA; PATTERN;

D O I：

10.1192/bjp.bp.110.085944

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Our aim was to investigate whether there is a season-of-birth effect in anorexia nervosa. In a meta-analysis, we compared the distribution of anorexia births (n = 1293) from four independent UK cohorts to that of the general UK population (n=21 914 037), using both the Walter & Elwood seasonality and chi-squared tests. We found an excess of anorexia births from March to June (odds ratio (OR)= 1.15, 95% Cl 1.03-1.29, P=0.012) and a deficit from September to October (OR=0.8, 95% Cl 0.68-0.94, P=0.007). These results indicate that environmental risk factor(s) are operative during gestation or immediately after birth and their identification will be important for disease prevention strategies.

引用

页码：404 / 405

页数：2

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