8-fluoro-4-hydroxy-1H-[1,2,4]triazino[4,5-a]quinoline-1,6(2H)-dione:: synthesis and reactivity

被引：3

作者：

Edmont, D ^{[1
]}

Chenault, J ^{[1
]}

机构：

[1] Univ Orleans, Inst Chim Organ & Analyt, F-45067 Orleans 2, France

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2003年 / 40卷 / 05期

关键词：

D O I：

10.1002/jhet.5570400507

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and versatile methodology to synthesise 4-hydroxy-1H-[1,2,4]triazino[4,5-a]quinotine-1,6(2H)-dione from methyl 6-fluoro-4-oxo-1,4-dihydro-2-quinolinecarboxylate has been developed. It involves carbohydrazide formation followed by a condensation with triphosgene to form the fused [1,2,4]triazino ring. In addition, the reactivity of the [1,2,4]triazino ring has been studied.

引用

页码：789 / 793

页数：5

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