Potent Anti-Platelet Constituents from Centaurea iberica

被引：17

作者：

Khan, Amna Nisar ^{[1
]}

Fatima, Itrat ^{[1
]}

Khaliq, Urooj Abdul ^{[1
]}

Malik, Abdul ^{[1
]}

Miana, Ghulam Abbas ^{[2
]}

Qureshi, Zia-ur-Rehman ^{[3
]}

Rasheed, Huma ^{[3
]}

机构：

[1] Univ Karachi, Int Ctr Chem & Biol Sci, HEJ Res Inst Chem, Karachi 75270, Pakistan

[2] Riphah Int Univ, Riphah Inst Pharmaceut Sci, Islamabad, Pakistan

[3] Univ Karachi, Int Ctr Chem & Biol Sci, Dr Panjwani Ctr Mol Med & Drug Res, Karachi 75270, Pakistan

来源：

MOLECULES | 2011年 / 16卷 / 03期

关键词：

Centaurea iberica; nitrogenous compounds; dimeric lignan glucoside; anti platelet activity; MEDICINAL-PLANTS; GROWING WILD; CHEMISTRY; LIGNANS;

D O I：

10.3390/molecules16032053

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

New naturally occurring nitrogenous compounds 1 and 2, along with a new dimeric lignan glucoside 3, have been isolated from the ethyl acetate soluble fraction of Centaurea iberica. Their structures have been elucidated through spectroscopic techniques. All the isolated compounds showed significant platelet aggregation inhibition.

引用

页码：2053 / 2064

页数：12

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