Portal vein stenting as a significant risk factor for biliary stricture in adult living donor liver transplantation

被引：1

作者：

Shin, Min-Ho ^{[1
]}

Moon, Deok-Bog ^{[1
]}

Lee, Sung-Gyu ^{[1
]}

Hwang, Shin ^{[1
]}

Kim, Ki-Hun ^{[1
]}

Ahn, Chul-Soo ^{[1
]}

Ha, Tae-Yong ^{[1
]}

Song, Gi-Won ^{[1
]}

Jung, Dong-Hwan ^{[1
]}

Park, Gil-Chun ^{[1
]}

Yun, Young-In ^{[1
]}

Kim, Wan-Jun ^{[1
]}

Kang, Woo-Hyoung ^{[1
]}

Kim, Seok-Hwan ^{[1
]}

Ko, Gi-Young ^{[2
]}

机构：

[1] Univ Ulsan, Coll Med, Asan Med Ctr,Dept Surg, Div Hepatobiliary Surg & Liver Transplantat, 88 Olymp Ro 43 Gil, Seoul 05505, South Korea

[2] Univ Ulsan, Coll Med, Asan Med Ctr,Dept Surg, Dept Radiol & Res,Inst Radiol, 88 Olymp Ro 43 Gil, Seoul 05505, South Korea

来源：

HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL | 2016年 / 15卷 / 05期

关键词：

portal vein stenting; biliary stricture; living donor liver transplantation; SPONTANEOUS PORTOSYSTEMIC COLLATERALS; VASCULAR COMPLICATIONS; ANASTOMOTIC STRICTURE; MANAGEMENT; RECONSTRUCTION; THROMBOSIS; CHALLENGES; STRATEGIES; PLACEMENT;

D O I：

10.1016/S1499-3872(16)60126-1

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

BACKGROUND: Although perioperative portal vein (PV) stent implantation is an effective treatment for steno-occlusive disease in adult living donor liver transplantation (LDLT) recipients, we experienced high incidence of biliary anastomotic strictures (BAS) after PV stenting. In this study, we sought to clarify the relation between BAS and PV stenting and to suggest the possible mechanism of BAS and measures to reduce its incidence. METHODS: We retrospectively analyzed 44 LDLT recipients who underwent PV stent implantation across the line of PV anastomosis regardless of the location of steno-occlusion (stent group) and their matched controls (non-stented LDLT recipients, n=131). RESULTS: The incidence of BAS was higher in patients in the stent group than that in the control group (43.2% vs 17.6%, P=0.001). Cumulative 6-month and 1-, 2- and 5-year BAS rates were 31.8%, 34.1%, 41.4% and 43.2%, respectively, in the stent group and 13.0%, 13.8%, 16.1% and 17.8%, respectively, in the control group (P=0.001). Multivariate analysis revealed that PV stenting was an independent risk factor for BAS. CONCLUSIONS: Although PV stent implantation is a reliable treatment modality for steno-occlusive PV in adult LDLT recipients, innovative methods to prevent the PV stent from crossing the line of PV anastomosis may be necessary to reduce the incidence of postoperative BAS.

引用

页码：480 / 486

页数：7

共 25 条

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