Axillary nodal yields: A comparison between primary clearance and completion clearance after sentinel lymph node biopsy in the management of breast cancer

被引：6

作者：

Chakravorty, A. ^{[1
]}

Sanmugalingam, N. ^{[1
]}

Shrestha, A. ^{[1
]}

Thomee, E. ^{[1
]}

Rusby, J. ^{[1
]}

Roche, N. ^{[1
]}

MacNeill, F. ^{[1
]}

机构：

[1] Royal Marsden Hosp, Acad Surg Unit, London SW3 6JJ, England

来源：

EJSO | 2011年 / 37卷 / 02期

关键词：

Sentinel node biopsy; Intra-operative assessment; Breast cancer; Nodal yield; AMERICAN-COLLEGE; DISSECTION; CYTOLOGY; Z0011;

D O I：

10.1016/j.ejso.2010.10.005

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Aims: Axillary nodal status is the most important prognostic indicator which in turn influences adjuvant therapy and long term outcomes. The aim of this study was to compare total nodal yields from primary axillary lymph node dissection (pALND) with completion ALND after a cancer positive SLNB: either concurrently (cALND) following intra-operative assessment (IOA) of the SLN's or as a delayed procedure (dALND) when the SLN was found to be cancer positive on post-operative histological examination. Methods: All axillary procedures performed between May 2006 and September 2009 were identified from a prospective database and categorised into four groups: SLNB with no further axillary surgery, pALND, cALND and dALND. Total nodal yield was the sum of SLN/s and ALND yields. Results: Of 1025 axillary procedures, ALND accounted for 332 (32.4%) of which 207 (62.3%) underwent pALND, 43 (12.9%) cALND, and 82 (24.6%) dALND. Median nodal yields were 15.0, 16.0 and 14.5 respectively (p = 0.3). Conclusion: Total nodal yields for primary, concurrent and delayed ALND were comparable suggesting completion dALND performed as a second operation does not compromise axillary staging. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：122 / 126

页数：5

共 19 条

[1]

[Anonymous], 2009, EUR J SURG ONCOL S1, V35, P1

[2] AXILLARY DISSECTION OF LEVEL-I AND LEVEL-II LYMPH-NODES IS IMPORTANT IN BREAST-CANCER CLASSIFICATION [J].

AXELSSON, CK ;

MOURIDSEN, HT ;

ZEDELER, K .

EUROPEAN JOURNAL OF CANCER, 1992, 28A (8-9) :1415-1418

[3] Axillary node staging by ultrasonography and fine-needle aspiration cytology in patients with breast cancer [J].

Baruah, B. P. ;

Goyal, A. ;

Young, P. ;

Douglas-Jones, A. G. ;

Mansel, R. E. .

BRITISH JOURNAL OF SURGERY, 2010, 97 (05) :680-683

[4] Preceding Sentinel Node Biopsy in Early Breast Cancer : Does it Affect the Number of Axillary Lymph Nodes ? [J].

Braems, G. ;

Denys, H. ;

Cocquyt, V. ;

Van den Broecke, R. .

ACTA CHIRURGICA BELGICA, 2008, 108 (06) :691-695

[5]

BYRNE B, 2009, EUR J SURG ONCOL, V35, P1234

[6] Predictors of non-sentinel lymph node metastasis in breast cancer patients [J].

Goyal, A ;

Douglas-Jones, A ;

Newcombe, RG ;

Mansel, RE .

EUROPEAN JOURNAL OF CANCER, 2004, 40 (11) :1731-1737

[7]

GUILIANO AE, 2010, J CLIN ONCOL S, V28, pS18

[8] Sentinel node biopsy in breast cancer [J].

Hindie, E. ;

Groheux, D. ;

Espie, M. ;

Bourstyn, E. ;

Toubert, M. -E. ;

Sarandi, F. ;

de Roquancourt, A. ;

Giacchetti, S. ;

Cuvier, C. ;

Cahen-Doidy, L. ;

Teyton, P. ;

Misset, J. -L. ;

Maylin, C. ;

Moretti, J. -L. .

BULLETIN DU CANCER, 2009, 96 (06) :713-725

[9] Testing the feasibility of intra-operative sentinel lymph node touch imprint cytology [J].

Jahromi, Alireza Hamidian ;

Narayanan, Sankaran ;

MacNeill, Fiona ;

Osin, Peter ;

Nerurkar, Ashutash ;

Gui, Gerald .

ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND, 2009, 91 (04) :336-339

[10] Establishing axillary Sentinel Lymph Node Biopsy (SLNB) for early breast cancer in the United Kingdom: A survey of the national training program [J].

Keshtgar, M. ;

Aresti, N. ;

MacNeil, F. .

EJSO, 2010, 36 (04) :393-398

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