Titanium(IV)-catalyzed dynamic kinetic asymmetric transformation of alcohols, silyl ethers, and acetals under carbon allylation

被引：102

作者：

Braun, M ^{[1
]}

Kotter, W ^{[1
]}

机构：

[1] Univ Dusseldorf, Inst Organ & Makromol Chem, D-40225 Dusseldorf, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 04期

关键词：

allylation; asymmetric catalysis; C-C coupling; Lewis acids; nucleophilic substitution;

D O I：

10.1002/anie.200352128

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

High yields and enantioselectivities are obtained in a dynamic kinetic asymmetric transformation in which the C-O bond of alcohols, silyl ethers, and acetals are substituted by a C-C bond. For example, the racemic indanyl silyl ether 1 is converted into (S)-2 in the presence of the chiral Lewis acidic TiIV complex 3.

引用

页码：514 / 517

页数：4

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