Hand eczema: treatment

被引:43
作者
Elsner, P. [1 ]
Agner, T. [2 ]
机构
[1] Univ Hosp Jena, Dept Dermatol, Jena, Germany
[2] Univ Copenhagen, Bispebjerg Hosp, Dept Dermatol, Copenhagen, Denmark
关键词
QUALITY-OF-LIFE; TOPICAL CORTICOSTEROIDS; ATOPIC-DERMATITIS; DOUBLE-BLIND; DRUG SURVIVAL; EFFICACY; ALITRETINOIN; SKIN; AZATHIOPRINE; MULTICENTER;
D O I
10.1111/jdv.16062
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Hand eczema is a highly prevalent, multietiological disease with a wide spectrum of severity and chronicity. The treatment of hand eczema, especially in severe and chronic cases, is a challenge to the dermatologist requiring not only diagnostic and therapeutic, but also excellent patient communication skills. This review discusses the spectrum of therapeutic options for hand eczema, the evidence for their efficacy and safety, and proposes a stepwise approach of intensity of treatment depending on disease severity and chronicity. In the near future, hand eczema patients may benefit from new therapeutic principles such as biologics for the treatment of atopic eczema and topical Janus Kinase inhibitors.
引用
收藏
页码:13 / 21
页数:9
相关论文
共 86 条
[1]  
Agner T, 2020, J EUR ACAD DERMATOL, V34, P13
[2]   Hand Dermatitis: A Review of Clinical Features, Prevention and Treatment [J].
Antonov, Dimitar ;
Schliemann, Sibylle ;
Elsner, Peter .
AMERICAN JOURNAL OF CLINICAL DERMATOLOGY, 2015, 16 (04) :257-270
[3]   Chronic hand eczema in Germany: 5-year follow-up data from the CARPE registry [J].
Apfelbacher, Christian J. ;
Ofenloch, Robert F. ;
Weisshaar, Elke ;
Molin, Sonja ;
Bauer, Andrea ;
Mahler, Vera ;
Heinrich, Andreas ;
von Kiedrowski, Ralph ;
Schmitt, Jochen ;
Elsner, Peter ;
Diepgen, Thomas L. .
CONTACT DERMATITIS, 2019, 80 (01) :45-53
[4]   Characteristics and Provision of Care in Patients with Chronic Hand Eczema: Updated Data from the CARPE Registry [J].
Apfelbacher, Christian J. ;
Molin, Sonja ;
Weisshaar, Elke ;
Bauer, Andrea ;
Elsner, Peter ;
Mahler, Vera ;
Weiss, Melanie ;
Ruzicka, Thomas ;
Diepgen, Thomas L. .
ACTA DERMATO-VENEREOLOGICA, 2014, 94 (02) :163-167
[5]   CARPE: a registry project of the German Dermatological Society (DDG) for the characterization and care of chronic hand eczema [J].
Apfelbacher, Christian Joachim ;
Akst, Wilhelm ;
Molin, Sonja ;
Schmitt, Jochen ;
Bauer, Andrea ;
Weisshaar, Elke ;
Mahler, Vera ;
Treichel, Sabine ;
Ruzicka, Thomas ;
Luger, Thomas ;
Elsner, Peter ;
Diepgen, Thomas Ludwig .
JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2011, 9 (09) :682-688
[6]   Diagnostics and treatment of the xerosis cutis - a position paper [J].
Augustin, Matthias ;
Wilsmann-Theis, Dagmar ;
Koerber, Andreas ;
Kerscher, Martina ;
Itschert, Goetz ;
Dippel, Michaela ;
Staubach, Petra .
JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2018, 16 :3-35
[7]   Impact on quality of life of alitretinoin in severe chronic hand eczema: FUGETTA real-world study [J].
Augustin, Matthias ;
Thaci, Diamant ;
Kamps, Anja .
JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2016, 14 (12) :1261-1270
[8]   Efficacy of pimecrolimus 1 % cream in the long term management of atopic hand dermatitis. A double-blind RCT [J].
Bauer, Andrea ;
Lange, Nora ;
Matterne, Uwe ;
Meurer, Michael ;
Braeutigam, Matthias ;
Diepgen, Thomas L. .
JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2012, 10 (06) :426-433
[9]  
Belsito DV, 2004, CUTIS, V73, P31
[10]   Chronic hand eczema: A prospective analysis of the Swiss CARPE registry focusing on factors associated with clinical and quality of life improvement [J].
Cazzaniga, Simone ;
Ballmer-Weber, Barbara K. ;
Grani, Nora ;
Spring, Philippe ;
Bircher, Andreas ;
Anliker, Mark ;
Sonntag, Anne-Katharina ;
Piletta, Pierre ;
Huber, Caroline ;
Diepgen, Thomas L. ;
Apfelbacher, Christian ;
Naldi, Luigi ;
Borradori, Luca ;
Simon, Dagmar .
CONTACT DERMATITIS, 2018, 79 (03) :136-148