Synthesis of a new, highly fluorescent amino acid derivative:: N-[(tert-butoxy)carbonyl]-3-[2-(1H-indol-3-yl)benzoxazol-5-yl]-L-alanine methyl ester

被引：0
|
作者：
Guzow, K [1 ]
Szabelski, M [1 ]
Malicka, J [1 ]
Wiczk, W [1 ]
机构：
[1] Univ Gdansk, Fac Chem, PL-80952 Gdansk, Poland
来源：
HELVETICA CHIMICA ACTA | 2001年 / 84卷 / 05期
关键词：
D O I：
10.1002/1522-2675(20010516)84:5<1086::AID-HLCA1086>3.0.CO;2-D
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A simple method of synthesis of a new. highly fluorescent amino acid derivative from the simple and generally available substrates 3-nitro-L-tyrosine and 1H-indole-3-carbaldehyde is described. The obtained compound, N-[(tert-butoxy)carbonyl]-3-[2-(1H-indol-3-yl)benzoxazol-5-yl]-L-alanine methyl ester (4), possesses a high fluorescence quantum yield. The described method illustrates a new possibility of synthesis of amino acid derivatives possessing desirable photophysical properties.
引用
收藏
页码：1086 / 1092
页数：7
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