Constraints on somatosensory map development: mutants lead the way

被引:5
作者
Gaspart, Patricia [1 ,2 ]
Renier, Nicolas [2 ,3 ]
机构
[1] Inst Fer Moulin, INSERM, U839, Paris, France
[2] Sorbonne Univ, Paris, France
[3] Hop La Pitie Salpetriere, Inst Cerveau & Moelle Epiniere ICM, INSERM, CNRS, Paris, France
关键词
BARREL CORTEX; CEREBRAL-CORTEX; SENSORY INPUT; LAYER-IV; ESTABLISHMENT; EXPRESSION; MATURATION; PLASTICITY; EVOLUTION; PATTERNS;
D O I
10.1016/j.conb.2018.04.028
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
In the rodent somatosensory system, the disproportionally large whisker representation and their specialization into barrel-shaped units in the different sensory relays has offered experimentalists with an ideal tool to identify mechanisms involved in brain map formation. These combine three intertwined constraints: Firstly, fasciculation of the incoming axons; secondly, early neural activity; finally, molecular patterning. Sophisticated genetic manipulations in mice have now allowed dissecting these mechanisms with greater accuracy. Here we discuss some recent papers that provided novel insights into how these different mapping rules and constraints interact to shape the barrel map.
引用
收藏
页码:43 / 49
页数:7
相关论文
共 39 条
  • [1] The Nature of the Sensory Input to the Neonatal Rat Barrel Cortex
    Akhmetshina, Dinara
    Nasretdinov, Azat
    Zakharov, Andrei
    Valeeva, Guzel
    Khazipov, Roustem
    [J]. JOURNAL OF NEUROSCIENCE, 2016, 36 (38) : 9922 - 9932
  • [2] NON-DECUSSATING RETINAL-FUGAL FIBER SYNDROME - AN INBORN ACHIASMATIC MALFORMATION ASSOCIATED WITH VISUOTOPIC MISROUTING, VISUAL-EVOKED POTENTIAL IPSILATERAL ASYMMETRY AND NYSTAGMUS
    APKARIAN, P
    BOUR, LJ
    BARTH, PG
    WENNIGERPRICK, L
    VERBEETEN, B
    [J]. BRAIN, 1995, 118 : 1195 - 1216
  • [3] Thalamic NMDA Receptor Function Is Necessary for Patterning of the Thalamocortical Somatosensory Map and for Sensorimotor Behaviors
    Arakawa, Hiroyuki
    Suzuki, Ayumi
    Zhao, Shuxin
    Tsytsarev, Vassiliy
    Lo, Fu-Sun
    Hayashi, Yu
    Itohara, Shigeyoshi
    Iwasato, Takuji
    Erzurumlu, Reha S.
    [J]. JOURNAL OF NEUROSCIENCE, 2014, 34 (36) : 12001 - 12014
  • [4] Maturation of cortical circuits requires Semaphorin 7A
    Carcea, Ioana
    Patil, Shekhar B.
    Robison, Alfred J.
    Mesias, Roxana
    Huntsman, Molly M.
    Froemke, Robert C.
    Buxbaum, Joseph D.
    Huntley, George W.
    Benson, Deanna L.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (38) : 13978 - 13983
  • [5] Catania KC, 1997, J COMP NEUROL, V387, P215
  • [6] Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-β signaling
    da Silva, Susana
    Hasegawa, Hiroshi
    Scott, Alexandra
    Zhou, Xiang
    Wagner, Amanda K.
    Han, Bao-Xia
    Wang, Fan
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (08) : 3395 - 3400
  • [7] Development and critical period plasticity of the barrel cortex
    Erzurumlu, Reha S.
    Gaspar, Patricia
    [J]. EUROPEAN JOURNAL OF NEUROSCIENCE, 2012, 35 (10) : 1540 - 1553
  • [8] Mapping the face in the somatosensory brainstem
    Erzurumlu, Reha S.
    Murakami, Yasunori
    Rijli, Filippo M.
    [J]. NATURE REVIEWS NEUROSCIENCE, 2010, 11 (04) : 252 - 263
  • [9] Input-dependent regulation of excitability controls dendritic maturation in somatosensory thalamocortical neurons
    Frangeul, Laura
    Kehayas, Vassilis
    Sanchez-Mut, Jose V.
    Fievre, Sabine
    Krishna-K, K.
    Pouchelon, Gabrielle
    Telley, Ludovic
    Bellone, Camilla
    Holtmaat, Anthony
    Graff, Johannes
    Macklis, Jeffrey D.
    Jabaudon, Denis
    [J]. NATURE COMMUNICATIONS, 2017, 8
  • [10] A cross-modal genetic framework for the development and plasticity of sensory pathways
    Frangeul, Laura
    Pouchelon, Gabrielle
    Telley, Ludovic
    Lefort, Sandrine
    Luscher, Christian
    Jabaudon, Denis
    [J]. NATURE, 2016, 538 (7623) : 96 - +