Self-assembly of novel cholesterol derivative based on hydrogen bond

In this paper, a novel cholesterol derivative was found that it can form regular arrangement with millimeter size when we investigated the synthesis of new cholesterol monomer. The quite interesting thing is that the arrangement can form on common glass sheet after the sample is heating above its melting point and then cooling to room temperature. This is different from most reported regular arrangements formed in solutions. According to the single crystal results of the sample, we believe that the arrangement formed in solid state can be attributed to hydrogen bonding formed between molecular and van der Waals force among molecular. (C) 2011 Elsevier B.V. All rights reserved.