BIOMARKERS FOR DIABETES COMPLICATIONS: THE RESULTS OF SEVERAL CLINICAL STUDIES

被引：9

作者：

Aslan, Diler ^{[1
]}

机构：

[1] Pamukkale Univ, Sch Med, Dept Med Biochem, Denizli, Turkey

来源：

JOURNAL OF MEDICAL BIOCHEMISTRY | 2011年 / 30卷 / 03期

关键词：

diabetes; biomarkers; clinical studies; HEPATOCYTE GROWTH-FACTOR; URINARY BIOMARKERS; GENE POLYMORPHISMS; OXIDATIVE STRESS; DISEASE; ASSOCIATION; MELLITUS; RISK; NEPHROPATHY; MORTALITY;

D O I：

10.2478/v10011-011-0024-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Diabetes is a common metabolic disorder. Its microvascular and macrovascular complications contribute to death, disabilities, and reduction in life expectancy in diabetes. It is a costly disease, and affects not only the patient and family, but also the public health, communities and society. It takes an increasing proportion of the national health care expenditure. The prevention of the development of diabetes and its complications is a major concern. Biomarkers have been investigated for understanding the mechanisms of the development and progression of diabetic complications. In this paper, the biomarkers which are recommended in the clinical practice and laboratory medicine guidelines, and which have been investigated for prediction or diagnosis of diabetes complications, have been reviewed. The results of several clinical studies will be summarized.

引用

页码：207 / 212

页数：6

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