Juvenile-onset OCD: clinical features in children, adolescents and adults

被引:76
作者
Mancebo, M. C. [1 ,2 ]
Garcia, A. M. [2 ,3 ]
Pinto, A. [1 ,2 ]
Freeman, J. B. [2 ,3 ]
Przeworski, A. [2 ,3 ]
Stout, R. [2 ]
Kane, J. S. [2 ]
Eisen, J. L. [2 ]
Rasmussen, S. A. [1 ,2 ]
机构
[1] Butler Hosp, Providence, RI 02906 USA
[2] Brown Univ, Dept Psychiat & Human Behav, Warren Alpert Med Sch, Providence, RI 02912 USA
[3] Bradley Hasbro Res Ctr, Providence, RI USA
关键词
obsessive-compulsive disorder; age at onset; children; adults; phenomenology;
D O I
10.1111/j.1600-0447.2008.01224.x
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective: To examine clinical correlates of juvenile-onset OCD across the lifespan. Method: Data collected at the intake interview from 257 consecutive participants with juvenile-onset OCD (20 children, 44 adolescents and 193 adults) in a naturalistic study of the clinical course of OCD were examined. Participants and parents of juvenile participants completed a structured diagnostic interview, rater-administered severity measures and self-report questionnaires. Results: Children and adolescents (i.e. juveniles) shared similar features with the exception of age at onset and OCD symptom expression. Clinically meaningful differences between juvenile and adult participants were also found. Compared with adults, juveniles were more likely to be male, recall an earlier age at OCD onset and have different lifetime comorbidity patterns. Conclusion: Juvenile-onset OCD symptom expression is remarkably similar across the lifespan. However, findings also suggest clinically meaningful differences between juveniles and adults. Future work using a prospective design will improve our understanding of course patterns of juvenile-onset OCD.
引用
收藏
页码:149 / 159
页数:11
相关论文
共 49 条
[1]  
Albert Umberto, 2002, Epidemiol Psichiatr Soc, V11, P116
[2]   Precision, reliability and accuracy in the dating of symptom onsets in child and adolescent psychopathology [J].
Angold, A ;
Erkanli, A ;
Costello, EJ ;
Rutter, M .
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY, 1996, 37 (06) :657-664
[3]  
[Anonymous], 1985, PSYCHOPHARMACOL BULL
[4]  
[Anonymous], 1998, Obsessive-Compulsive Disorders: Practical Management
[5]  
[Anonymous], 2000, DIAGN STAT MAN MENT, DOI DOI 10.1176/APPI.BOOKS.9780890425787
[6]   Early-onset obsessive-compulsive disorder: a subgroup with a specific clinical and familial pattern? [J].
Chabane, N ;
Delorme, R ;
Millet, B ;
Mouren, MC ;
Leboyer, M ;
Pauls, D .
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY, 2005, 46 (08) :881-887
[7]   Use of factor analysis to detect potential phenotypes in obsessive-compulsive disorder [J].
Denys, D ;
de Geus, F ;
van Megen, HJGM ;
Westenberg, HGM .
PSYCHIATRY RESEARCH, 2004, 128 (03) :273-280
[8]  
Diniz JB, 2004, J CLIN PSYCHIAT, V65, P22
[9]   Adults with early-onset obsessive-compulsive disorder [J].
do Rosario-Campos, MC ;
Leckman, JF ;
Mercadante, MT ;
Shavitt, RG ;
Prado, HD ;
Sada, P ;
Zamignani, D ;
Miguel, EC .
AMERICAN JOURNAL OF PSYCHIATRY, 2001, 158 (11) :1899-1903
[10]   The Brown Assessment of Beliefs Scale: Reliability and validity [J].
Eisen, JL ;
Phillips, KA ;
Baer, L ;
Beer, DA ;
Atala, KD ;
Rasmussen, SA .
AMERICAN JOURNAL OF PSYCHIATRY, 1998, 155 (01) :102-108