The structure of mucins conditions the viscoelastic properties of the mucus gel

被引：3

作者：

Desseyn, J. L. ^{[1
]}

Demouveaux, Bastien ^{[1
]}

Gouyer, Valerie ^{[1
]}

Magnien, Mylene ^{[1
]}

Plet, Segolene ^{[1
]}

Gottrand, Frederic ^{[1
]}

Narita, Tetsuharu ^{[2
,3
]}

Desseyn, Jean-Luc ^{[1
]}

机构：

[1] Univ Lille, CHU Lille, LIRIC UMR 995, INSERM, F-59000 Lille, France

[2] UPMC Univ Paris 06, PSL Res Univ, Lab Sci & Ingn Matiere Molle, ESPCI Paris,CNRS UMR 7615, 10 Rue Vauquelin, F-75231 Paris 05, France

[3] Hokkaido Univ, Global Inst Collaborat Res & Educ, Global Stn Soft Matter, Sapporo, Hokkaido, Japan

来源：

M S-MEDECINE SCIENCES | 2018年 / 34卷 / 10期

关键词：

GLYCOSYLATION; RESISTANT; TERMINUS; RHEOLOGY; MODEL;

D O I：

10.1051/medsci/2018206

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：806 / 812

页数：7

共 38 条

[1] Dimerization of the human MUC2 mucin in the endoplasmic reticulum is followed by a N-glycosylation-dependent transfer of the mono- and dimers to the Golgi apparatus [J].

Asker, N ;

Axelsson, MAB ;

Olofsson, SO ;

Hansson, GC .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (30) :18857-18863

[2] Trefoil factor peptide 3 is positively correlated with the viscoelastic properties of the cervical mucus plug [J].

Bastholm, Sara K. ;

Samson, Mie H. ;

Becher, Naja ;

Hansen, Lea K. ;

Stubbe, Peter R. ;

Chronakis, Ioannis S. ;

Nexo, Ebba ;

Uldbjerg, Niels .

ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 2017, 96 (01) :47-52

[3] Role of the cystine-knot motif at the C-terminus of rat mucin protein Muc2 in dimer formation and secretion [J].

Bell, SL ;

Xu, GQ ;

Forstner, JF .

BIOCHEMICAL JOURNAL, 2001, 357 :203-209

[4] Globular structure of human ovulatory cervical mucus [J].

Brunelli, Roberto ;

Papi, Massimiliano ;

Arcovito, Giuseppe ;

Bompiani, Adriano ;

Castagnola, Massimo ;

Parasassi, Tiziana ;

Sampaolese, Beatrice ;

Vincenzoni, Federica ;

De Spirito, Marco .

FASEB JOURNAL, 2007, 21 (14) :3872-3876

[5] Rheology of gastric mucin exhibits a pH-dependent sol-gel transition [J].

Celli, Jonathan P. ;

Turner, Bradley S. ;

Afdhal, Nezam H. ;

Ewoldt, Randy H. ;

McKinley, Gareth H. ;

Bansil, Rama ;

Erramilli, Shyamsunder .

BIOMACROMOLECULES, 2007, 8 (05) :1580-1586

[6] Mucins: A biologically relevant glycan barrier in mucosal protection [J].

Corfield, Anthony P. .

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2015, 1850 (01) :236-252

[7] Cervical Mucus Properties Stratify Risk for Preterm Birth [J].

Critchfield, Agatha S. ;

Yao, Grace ;

Jaishankar, Aditya ;

Friedlander, Ronn S. ;

Lieleg, Oliver ;

Doyle, Patrick S. ;

McKinley, Gareth ;

House, Michael ;

Ribbeck, Katharina .

PLOS ONE, 2013, 8 (08)

[8] Secondary Structure and Glycosylation of Mucus Glycoproteins by Raman Spectroscopies [J].

Davies, Heather S. ;

Singh, Prabha ;

Deckert-Gaudig, Tanja ;

Deckert, Volker ;

Rousseau, Karine ;

Ridley, Caroline E. ;

Dowd, Sarah E. ;

Doig, Andrew J. ;

Pudney, Paul D. A. ;

Thornton, David J. ;

Blanch, Ewan W. .

ANALYTICAL CHEMISTRY, 2016, 88 (23) :11609-11615

[9] Gel-forming mucin interactome drives mucus viscoelasticity [J].

Demouveaux, Bastien ;

Gouyer, Valerie ;

Gottrand, Frederic ;

Narita, Tetsuharu ;

Desseyn, Jean-Luc .

ADVANCES IN COLLOID AND INTERFACE SCIENCE, 2018, 252 :69-82

[10] Custom modification in vivo of mucus properties Proof of concept and potential applications [J].

Desseyn, Jean-Luc ;

Gouyer, Valerie ;

Gottrand, Frederic .

M S-MEDECINE SCIENCES, 2015, 31 (12) :1063-1066

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