Recent development on the [5+2] cycloadditions and their application in natural product synthesis

被引：71

作者：

Gao, Kai ^{[1
]}

Zhang, Yong-Gang ^{[1
]}

Wang, Zhiming ^{[1
]}

Ding, Hanfeng ^{[1
,2
]}

机构：

[1] Taizhou Univ, Inst Med Nat Prod, Sch Adv Study, Taizhou 318000, Peoples R China

[2] Zhejiang Univ, Dept Chem, Hangzhou 310058, Zhejiang, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 13期

基金：

中国国家自然科学基金;

关键词：

RING-CLOSURE REACTIONS; PSEUDOLARIC ACID-B; VINYL AZIRIDINES; 7-MEMBERED RINGS; FACILE SYNTHESIS; INTERMOLECULAR CYCLOADDITIONS; ASYMMETRIC-SYNTHESIS; BIOMIMETIC SYNTHESIS; SELECTIVE CATALYST; TUMOR PROMOTERS;

D O I：

10.1039/c8cc09077g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The [5+2] cycloaddition is one kind of fascinating and powerful reaction to access seven-membered ring systems existing in complex natural products and pharmaceuticals. In this review, recent developments on the [5+2] cycloadditions and their application in the synthesis of complex natural products are discussed. A focus is given to the way in which the [5+2] cycloadditions have influenced the logical process of the synthesis. This article is organized by reaction types, aiming to provide a clear clue to the latest research trends.

引用

页码：1859 / 1878

页数：20

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