Magnetic biochips: a new option for sensitive diagnostics

被引：123

作者：

Megens, M ^{[1
]}

Prins, M ^{[1
]}

机构：

[1] Philips Res Labs, NL-5656 AA Eindhoven, Netherlands

来源：

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 2005年 / 293卷 / 01期

关键词：

biosensor; medical diagnostics; giant magneto-resistance effect; magnetic actuation; integration; microdevices; assays; magnetic sensor; BARC; dynabeads; microchip;

D O I：

10.1016/j.jmmm.2005.02.046

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

We present an overview of miniaturized biosensor devices based on the sensitive detection of magnetic nanoparticles using the giant magneto-resistance effect. This detection principle has advantages over established methods, and the sensitivity is promising. In our opinion, the challenge is now in the integration-of sample pretreatment, in a cartridge, of nanoparticles with proper stabilization, magnetic properties, and surface functionalizations. (c) 2005 Published by Elsevier B.V.

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收藏

页码：702 / 708

页数：7

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