Increased Mortality Among Patients With Acute Leukemia Admitted on Weekends Compared to Weekdays

被引:4
|
作者
Parikh, Kaushal [1 ,2 ]
Shah, Mahek [3 ]
Mehta, Dhruv [1 ,2 ]
Arora, Shilpkumar [4 ]
Patel, Nilay [5 ]
Liu, Delong [1 ,2 ]
机构
[1] New York Med Coll, Dept Med, Valhalla, NY 10595 USA
[2] Westchester Med Ctr, Valhalla, NY USA
[3] Lehigh Valley Hosp, Dept Cardiol, Allentown, PA USA
[4] Mt Sinai St Lukes Roosevelt Hosp, Dept Med, New York, NY USA
[5] St Peters Univ Hosp, Dept Med, New Brunswick, NJ USA
来源
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | 2017年 / 17卷 / 12期
关键词
ICD-9-DM; Leukemia; Mortality; NIS; Outcome; ACUTE LYMPHOBLASTIC-LEUKEMIA; IN-HOSPITAL MORTALITY; MINIMAL RESIDUAL DISEASE; LENGTH-OF-STAY; BONE-MARROW; ADMISSION; ASSOCIATION; RISK; CHEMOTHERAPY; OUTCOMES;
D O I
10.1016/j.clml.2017.07.256
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The mortality of patients admitted on the weekends was compared with that on weekdays. There was significantly increased mortality among acute leukemia patients admitted on a weekend. We also conclude that patients admitted to teaching hospitals have a better outcome. This study emphasizes the importance of availability of resources and early presentation to tertiary care centers for acute leukemia patients. Background: The association between weekend admission and patient outcomes has been reported in several acute illnesses but is unknown in acute leukemia. Patients and Methods: We used the 2002 to 2014 Nationwide Inpatient Sample to identify patients admitted with a primary diagnosis of acute leukemia. Admissions were classified as weekend or weekday admissions for comparison. Hierarchical logistic regression models were used to analyze predictors of hospital mortality. Results: There was a 22.3% decline in acute leukemia admissions in 2014 compared to 2002 and a 4% decline in in-hospital mortality (19.0%-14.9%; P< .001). A total of 82,833 admissions were included in the study, and 14,241 (17.19%) occurred over the weekend. Hospital mortality was higher for weekend than weekday admissions (18.8% vs. 16.1%; P< .001). Weekend admissions were less likely to undergo early bone marrow biopsy than their weekday counterparts (27.5% vs. 46.3%; P-' .01). Bone marrow biopsy (adjusted odds ratio 0.36; 95% confidence interval [Cl], 0.33-0.39; P< .001) and admission to a teaching hospital (adjusted odds ratio, 0.65; 95% Cl, 0.56-0.75; P-' .001) independently predicted lower hospital mortality. Weekend admission was associated with higher hospital mortality (adjusted odds ratio, 1.12; 95 Cl, 1.02-1.23; P-.01) and more complications (50.6% vs. 47.8%; P< .001) than weekday admissions. Conclusion: There was significantly increased mortality among weekend admissions for acute leukemia. Mortality was reduced among patients admitted to teaching hospitals.
引用
收藏
页码:E33 / E43
页数:11
相关论文
共 50 条
  • [31] Adherence to lung protective mechanical ventilation in patients admitted to a surgical intensive care unit and the associated increased mortality
    Piriyapatsom, Annop
    Trisukhonth, Ajana
    Chintabanyat, Ornin
    Chaiwat, Onuma
    Kongsayreepong, Suneerat
    Thanakiattiwibun, Chayanan
    HELIYON, 2024, 10 (04)
  • [32] Outcome of severe head injured patients admitted to intensive care during weekday shifts compared to nights and weekends
    Lee, Kah Keow
    Ng, Ivan
    Ang, Beng Ti
    ANNALS ACADEMY OF MEDICINE SINGAPORE, 2008, 37 (05) : 390 - 396
  • [33] Higher mortality in patients hospitalized for acute aortic rupture or dissection during weekends
    Gallerani, Massimo
    Imberti, Davide
    Bossone, Eduardo
    Eagle, Kim A.
    Manfredini, Roberto
    JOURNAL OF VASCULAR SURGERY, 2012, 55 (05) : 1247 - 1254
  • [34] Comparing mortality risk of patients with acute hip fractures admitted to a major trauma centre on a weekday or weekend
    Nandra, Rajpal
    Pullan, Jack
    Bishop, Jonathan
    Baloch, Khalid
    Grover, Liam
    Porter, Keith
    SCIENTIFIC REPORTS, 2017, 7
  • [35] Treatment, Clinical Outcomes, and Predictors of Mortality among a National Cohort of Admitted Patients with Acinetobacter baumannii Infection
    Appaneal, Haley J.
    Lopes, Vrishali V.
    LaPlante, Kerry L.
    Caffrey, Aisling R.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2022, 66 (03)
  • [36] Mortality among patients admitted to intensive care units during weekday day shifts compared with "off" hours
    Luyt, Charles-Edouard
    Combes, Alain
    Aegerter, Philippe
    Guidet, Bertrand
    Trouillet, Jean-Louis
    Gibert, Claude
    Chastre, Jean
    CRITICAL CARE MEDICINE, 2007, 35 (01) : 3 - 11
  • [37] Mortality and Morbidity after Colostomy Reversal Among Patients admitted in Surgical Department
    Chhabrya, Rajesh Kumar
    Bilal, Muhmmad
    Rashid, Muhammad Javaid
    Sachdev, Sunil Dut
    Khan, Ishfaq Ahmad
    Khatri, Rekha
    JOURNAL OF RESEARCH IN MEDICAL AND DENTAL SCIENCE, 2022, 10 (01): : 285 - 289
  • [38] Increased Mortality in Hip Fracture Patients With Aortic Stenosis and Pulmonary Hypertension Compared to Aortic Stenosis Alone
    Cignoni, Christian B.
    Vuu, Steven K. M.
    Liu, Huazhi
    Clark, Jason M.
    Watson, Carrie D.
    Ferber, Laurence R.
    Richards, Winston T.
    Ang, Darwin N.
    AMERICAN SURGEON, 2023, 89 (05) : 1422 - 1430
  • [39] Impact of Obesity on In-Hospital Morbidity and Mortality Among Patients Admitted for Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)
    Bhide, Poorva
    Bapaye, Jay
    Mohan, Gaurav
    Ghose, Medha
    Ravilla, Jayashree
    Yarrarapu, Siva Naga S.
    Du, Doantrang
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2023, 15 (02)
  • [40] Increased mortality among patients taking digoxin-analysis from the AFFIRM study
    Whitbeck, Matthew G.
    Charnigo, Richard J.
    Khairy, Paul
    Ziada, Khaled
    Bailey, Alison L.
    Zegarra, Milagros M.
    Shah, Jignesh
    Morales, Gustavo
    Macaulay, Tracy
    Sorrell, Vincent L.
    Campbell, Charles L.
    Gurley, John
    Anaya, Paul
    Nasr, Hafez
    Bai, Rong
    Di Biase, Luigi
    Booth, David C.
    Jondeau, Guillaume
    Natale, Andrea
    Roy, Denis
    Smyth, Susan
    Moliterno, David J.
    Elayi, Claude S.
    EUROPEAN HEART JOURNAL, 2013, 34 (20) : 1481 - 1488