The determination of cobalt and chromium in whole blood sampled from metal-metal and metal-polyethylene hip articulation patients by DRC-ICP-MS

被引：0

作者：

Winship, P. D. ^{[1
]}

Faria, N. ^{[1
]}

Skinner, J. A. ^{[2
]}

Hart, A. J. ^{[3
]}

Powell, Jt ^{[1
]}

机构：

[1] MRC Human Nutr Res, 120 Fulbourn Rd, Cambridge CB1 9NL, England

[2] RoyaI Natl Orthopaed Hosp, Stanmore HA7 4LP, Middx, England

[3] Imperial Coll, Dept Musculoskeletal Surg, London SW7 2AZ, England

来源：

METAL IONS IN BIOLOGY AND MEDICINE, VOL 10 | 2008年 / 10卷

关键词：

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Inductively Coupled plasma mass spectrometry (ICP-MS) is widely used for the determination of cobalt and chromium in biological samples such as whole blood, however the presence of spectroscopic interference can complicate the measurement of certain isotopes. A robust analytical method was developed for the determination of Co and Cr concentration of whole blood sampled from 207 patients that have received a metal based hip articulation. The level of Co and Cr in these patient samples was considerably higher than that found in healthy volunteers.

引用

页码：27 / +

页数：2

共 6 条

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