Copper oxide nanoflakes as highly sensitive and fast response self-sterilizing biosensors

被引:119
作者
Akhavan, O. [1 ,2 ]
Ghaderi, E. [1 ]
机构
[1] Sharif Univ Technol, Dept Phys, Tehran, Iran
[2] Sharif Univ Technol, Inst Nanosci & Nanotechnol, Tehran, Iran
关键词
CUO NANOSTRUCTURES; THIN-FILMS; CARBON NANOTUBES; RAPID DETECTION; GLUCOSE SENSOR; CUPRIC OXIDE; BACTERIA; GROWTH; SURFACE; DEGRADATION;
D O I
10.1039/c1jm11813g
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Vertical copper oxide nanoflakes were synthesized on a Cu foil through oxidation in alkaline conditions. X-ray photoelectron spectroscopy showed that after exposing the nanoflakes to an Escherichia coli bacterial suspension, the outermost surface of the nanoflakes was chemically reduced through the glycolysis process of the bacteria. Current-voltage (I-V) characteristics of the nanoflakes (measured perpendicular to surface of the Cu foil by using conductive atomic force microscopy) indicated that electrical resistivity of the nanoflakes increased about one order of magnitude after exposure to the bacterial suspension. The nanoflakes reduced by the bacterial suspension could also be reoxidized by ex-situ NaOH treatment at 60 degrees C. The response time and recovery time of the bacterial sensor were measured as similar to 2 min. Furthermore, the lower detection limit of the sensor was found to be similar to 10(2) CFU mL(-1). The bacteria could also not survive on the nanoflakes. For example, after 30 min, 88 +/- 11 and 97 +/- 2% of the bacteria were inactivated on the surface of the as-prepares nanoflakes, in the dark and under light irradiation, respectively. Therefore, the copper oxide nanoflakes can be used as highly sensitive and fast response self-sterilizing biosensors for microorganisms contributing a glycolysis process.
引用
收藏
页码:12935 / 12940
页数:6
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