Low-Temperature Plasma for Biology, Hygiene, and Medicine: Perspective and Roadmap

被引：102

作者：

Laroussi, Mounir ^{[1
]}

Bekeschus, Sander ^{[2
]}

Keidar, Michael ^{[3
]}

Bogaerts, Annemie ^{[4
]}

Fridman, Alexander ^{[5
]}

Lu, Xinpei ^{[6
]}

Ostrikov, Kostya ^{[7
]}

Hori, Masaru ^{[8
]}

Stapelmann, Katharina ^{[9
]}

Miller, Vandana ^{[10
]}

Reuter, Stephan ^{[11
]}

Laux, Christophe ^{[12
]}

Mesbah, Ali ^{[13
]}

Walsh, James ^{[14
]}

Jiang, Chunqi ^{[15
]}

Thagard, Selma Mededovic ^{[16
]}

Tanaka, Hiromasa ^{[8
]}

Liu, Dawei ^{[6
]}

Yan, Dayun ^{[3
]}

Yusupov, Maksudbek ^{[4
,17
]}

机构：

[1] Old Dominion Univ, Elect & Comp Engn Dept, Norfolk, VA 23529 USA

[2] Leibnitz Inst Plasma Sci & Technol, ZIK Plasmatis, D-17489 Greifswald, Germany

[3] George Washington Univ, Mech & Aerosp Engn Dept, Washington, DC 20052 USA

[4] Univ Antwerp, Dept Chem, Res Grp PLASMANT, B-2610 Antwerp, Belgium

[5] Drexel Univ, Nyheim Plasma Inst, Philadelphia, PA 19104 USA

[6] Huazhong Univ Sci & Technol, Sch Elect & Elect Engn, Wuhan 430074, Hubei, Peoples R China

[7] Queensland Univ Technol, Sch Chem & Phys, Brisbane, Qld 4000, Australia

[8] Nagoya Univ, Ctr Low Temp Plasma Sci, Nagoya, Aichi 4648693, Japan

[9] North Carolina State Univ, Dept Nucl Engn, Raleigh, NC 27695 USA

[10] Drexel Univ Coll Med, Inst Mol Med & Infect Dis, Dept Microbiol & Immunol, Philadelphia, PA 19129 USA

[11] Polytech Montreal, Dept Engn Phys, Montreal, PQ H3T 1J4, Canada

[12] Univ Paris Saclay, Lab EM2C, CentraleSupelec, CNRS, F-91190 Paris, France

[13] Univ Calif Berkeley, Dept Chem & Biomol Engn, Berkeley, CA 94720 USA

[14] Univ Liverpool, Dept Elect Engn & Elect, Brownlow Hill, Liverpool L69 3GJ, Merseyside, England

[15] Old Dominion Univ, Frank Reidy Res Ctr Bioelect, Norfolk, VA 23529 USA

[16] Clarkson Univ, Dept Chem & Biomol Engn, Potsdam, NY 13676 USA

[17] Acad Sci Uzbek, Arifov Inst Ion Plasma & Laser Technol, Lab Thermal Phys Multiphase Syst, Tashkent 100125, Uzbekistan

来源：

IEEE TRANSACTIONS ON RADIATION AND PLASMA MEDICAL SCIENCES | 2022年 / 6卷 / 02期

基金：

英国工程与自然科学研究理事会;

关键词：

Bacteria; cancer; cold plasma; decontamination; plasma medicine; radicals; reactive species; wound healing; COLD ATMOSPHERIC PLASMA; BARRIER DISCHARGE PLASMA; IMMUNOGENIC CELL-DEATH; PRESSURE PLASMA; REACTIVE OXYGEN; ARGON PLASMA; INFLAMMATORY RESPONSE; NONEQUILIBRIUM PLASMA; FLUORESCENT-PROBES; NONTHERMAL PLASMA;

D O I：

10.1109/TRPMS.2021.3135118

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Plasma, the fourth and most pervasive state of matter in the visible universe, is a fascinating medium that is connected to the beginning of our universe itself. Man-made plasmas are at the core of many technological advances that include the fabrication of semiconductor devices, which enabled the modern computer and communication revolutions. The introduction of low temperature, atmospheric pressure plasmas to the biomedical field has ushered a new revolution in the healthcare arena that promises to introduce plasma-based therapies to combat some thorny and long-standing medical challenges. This article presents an overview of where research is at today and discusses innovative concepts and approaches to overcome present challenges and take the field to the next level. It is written by a team of experts who took an in-depth look at the various applications of plasma in hygiene, decontamination, and medicine, made critical analysis, and proposed ideas and concepts that should help the research community focus their efforts on clear and practical steps necessary to keep the field advancing for decades to come.

引用

页码：127 / 157

页数：31

共 299 条

[1] Virucidal Effect of Cold Atmospheric Gaseous Plasma on Feline Calicivirus, a Surrogate for Human Norovirus [J].