Can the Irradiated Brain Be Salvaged by Oligodendrocyte Precursor Transplantation?

被引:6
|
作者
Harrisingh, Marie C. [1 ]
Ffrench-Constant, Charles [1 ]
机构
[1] Univ Edinburgh, MRC Ctr Regenerat Med, Edinburgh EH16 4UU, Midlothian, Scotland
关键词
PROGENITOR CELLS; CNS;
D O I
10.1016/j.stem.2015.01.010
中图分类号
Q813 [细胞工程];
学科分类号
摘要
Radiotherapy is a mainstay of brain cancer treatment, but it causes significant complications. In this issue of Cell Stem Cell, Piao et al. (2015) derive oligodendrocyte precursors from human embryonic stem cells and show that engrafted cells replenish depleted precursor numbers, generate new myelin, and reverse behavioral defects in irradiated rats.
引用
收藏
页码:113 / 114
页数:2
相关论文
共 50 条
  • [21] OLIGODENDROCYTE PRECURSOR QUANTITATION AND LOCALIZATION IN PERINATAL BRAIN USING A RETROSPECTIVE BIOASSAY
    GONYE, GE
    WARRINGTON, AE
    DEVITO, JA
    PFEIFFER, SE
    JOURNAL OF NEUROSCIENCE, 1994, 14 (09): : 5365 - 5372
  • [22] Can Sexual Harassment be Salvaged?
    M. J. Booker
    Journal of Business Ethics, 1998, 17 : 1171 - 1177
  • [23] Minimally manipulated oligodendrocyte precursor cells retain exclusive commitment to the oligodendrocyte lineage following transplantation into intact and injured hippocampus
    Webber, Daniel J.
    Compston, Alastair
    Chandran, Siddharthan
    EUROPEAN JOURNAL OF NEUROSCIENCE, 2007, 26 (07) : 1791 - 1800
  • [24] Transplantation reveals regional differences in oligodendrocyte differentiation in the adult brain
    Francesca Viganò
    Wiebke Möbius
    Magdalena Götz
    Leda Dimou
    Nature Neuroscience, 2013, 16 : 1370 - 1372
  • [25] Transplantation reveals regional differences in oligodendrocyte differentiation in the adult brain
    Vigano, Francesca
    Moebius, Wiebke
    Goetz, Magdalena
    Dimou, Leda
    NATURE NEUROSCIENCE, 2013, 16 (10) : 1370 - +
  • [26] Can sexual harassment be salvaged?
    Booker, MJ
    JOURNAL OF BUSINESS ETHICS, 1998, 17 (11) : 1171 - 1177
  • [27] Can Drop Outs Be Salvaged?
    Leahy, Kathleen A.
    AMERICAN JOURNAL OF NURSING, 1943, 43 (10) : 897 - 898
  • [28] SUMMER PROGRAM - IT CAN BE SALVAGED
    LARK, FJ
    AGRICULTURAL EDUCATION, 1976, 48 (12): : 277 - &
  • [29] Can class analysis be salvaged?
    Grusky, DB
    Sorensen, JB
    AMERICAN JOURNAL OF SOCIOLOGY, 1998, 103 (05) : 1187 - 1234
  • [30] Aging compromises oligodendrocyte precursor cell maturation and efficient remyelination in the monkey brain
    Dimovasili, Christina
    Fair, Ashley E.
    Garza, Isabella R.
    Batterman, Katelyn, V
    Mortazavi, Farzad
    Moore, Tara L.
    Rosene, Douglas L.
    GEROSCIENCE, 2023, 45 (01) : 249 - 264