Salamanders and caecilians, neglected from the chemical point of view

被引：6

作者：

de Vasconcelos, Isadora Alves ^{[1
]}

de Souza, Jessica Oliveira ^{[1
]}

de Castro, Jessica Schneider ^{[1
]}

Correia de Santana, Carlos Jose ^{[1
,2
]}

Martins Magalhaes, Ana Carolina ^{[1
]}

Castro, Mariana de Souza ^{[1
,2
]}

Pires Junior, Osmindo Rodrigues ^{[1
]}

机构：

[1] Univ Brasilia, Dept Physiol Sci, Brasilia, DF, Brazil

[2] Univ Brasilia, Dept Cell Biol, Brasilia, DF, Brazil

来源：

TOXIN REVIEWS | 2022年 / 41卷 / 04期

关键词：

Salamanders; caecilians; toxins; skin secretion; bioactive compounds; RED-SPOTTED NEWT; CHINESE GIANT SALAMANDER; ROUGH-SKIN NEWT; SIPHONOPS-PAULENSIS GYMNOPHIONA; IONIZATION MASS-SPECTROMETRY; RESISTANT SODIUM-CHANNELS; TETRODOTOXIN LEVELS; TARICHA-GRANULOSA; DIE KONSTITUTION; AMPHIBIAN SKIN;

D O I：

10.1080/15569543.2021.1977326

中图分类号：

R99 [毒物学（毒理学）];

学科分类号：

100405 ;

摘要：

Amphibians are a rich source of biologically active molecules, but the majority of Toxinology scientific articles devoted themselves to investigating the anurans, given its worldwide distribution, abundance, and diversity. On the other hand, only 8.6% of Caudata species and 7.1% of Gymnophiona species have some study. This review brings the most fascinating biological activities from skin, skin secretions, and isolated components of Caudata and Gymnophiona species including taste aversion, adhesive secretion, toxic effect in animals, and cytotoxic activity as well as described molecules such as biogenic amines, tetrodotoxins, steroidal alkaloids, proteins, antimicrobial peptides, and pheromones.

引用

页码：1304 / 1332

页数：29

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