Phytogenic Nanoparticles to Combat Multi Drug Resistant Pathogens and Photocatalytic Degradation of Dyes

The present study reports the synthesis of silver nanoparticles using Sanguisorba officinalis. The synthesized nanoparticles were characterized using UV-visible spectrophotometry which displayed maximum absorbance at 427 nm. The FTIR analysis predicted the presence of hydroxyl, amine methyl, and carboxyl groups indicating the role of phyto-components to mediate the synthesis. The XRD studies revealed the crystalline nature of nanoparticles with Bragg's intensities at 2 theta angle. The morphological characteristics were studied with TEM analysis which displayed polydispersity of nanoparticles with average size between 10 and 50 nm. The antibacterial efficacy of nanoparticles was determined against multi-drug-resistant pathogens which resulted in highest activity against Ps. aeruginosa strain 215 and MRSA with 18 mm zone of inhibition. The minimal inhibitory concentration ranged between 250 and 500 mu g/ml to suppress the growth test pathogens. Photocatalytic degradation of safranin and crystal violet was studied using nanoparticles which resulted in rapid decolorization within 180 min of incubation time. Overall, the results obtained in the present investigation revealed the multi-applicative properties of nanoparticles to combat drug-resistant pathogens and catalytic activity against hazardous dyes.