NEURODEGENERATION An expansion in ALS genetics

被引：27

作者：

Lagier-Tourenne, Clotilde ^{[1
]}

Cleveland, Don W.

机构：

[1] Univ Calif San Diego, Ludwig Inst Canc Res, La Jolla, CA 92093 USA

来源：

NATURE | 2010年 / 466卷 / 7310期

基金：

英国惠康基金;

关键词：

AMYOTROPHIC-LATERAL-SCLEROSIS; FRONTOTEMPORAL LOBAR DEGENERATION; SPINOCEREBELLAR ATAXIA TYPE-2; TDP-43; MUTATIONS; CLONING; REPEAT;

D O I：

10.1038/4661052a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Aggregates and mutations of the proteins ataxin-2 and TDP-43 have been implicated in distinct neurodegenerative disorders. An interplay between these proteins is now reported for amyotrophic lateral sclerosis.

引用

页码：1052 / 1053

页数：2

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